CHODL
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Official Full Name
chondrolectin -
Overview
This gene encodes a type I membrane protein with a carbohydrate recognition domain characteristic of C-type lectins in;its extracellular portion. In other proteins, this domain is involved in endocytosis of glycoproteins and exogenous;sugar-bearing pathogens. This protein localizes predominantly to the perinuclear region. Several transcript variants;encoding a few different isoforms have been found for this gene. -
Synonyms
CHODL;chondrolectin;C21orf68;CHODL_HUMAN;Chromosome 21 open reading frame 68;FLJ12627;MT75;PRED12;Transmembrane protein MT75;UNQ872/PRO1890;3110074E07Rik
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- Rat
- E.coli
- Wheat Germ
- Mammalian Cell
- HEK293
- Human Cell
- HEK293T
- In Vitro Cell Free System
- His
- GST
- Fc
- Non
- Myc&DDK
Involved Pathway
CHODL involved in several pathways and played different roles in them. We selected most pathways CHODL participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CHODL were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
CHODL has several biochemical functions, for example, carbohydrate binding,NOT hyaluronic acid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CHODL itself. We selected most functions CHODL had, and list some proteins which have the same functions with CHODL. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| carbohydrate binding | KLRA8,ITLN1,CALR,MAN2A2,CD207,CHIA,REG3B,SFTPD,Clec4n,SIGLEC9 |
Interacting Protein
CHODL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHODL here. Most of them are supplied by our site. Hope this information will be useful for your research of CHODL.
Resources
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References
- Sleigh, JN; Barreiro-Iglesias, A; et al. Chondrolectin affects cell survival and neuronal outgrowth in in vitro and in vivo models of spinal muscular atrophy. HUMAN MOLECULAR GENETICS 23:855-869(2014).
- Zhong, Z; Ohnmacht, J; et al. Chondrolectin Mediates Growth Cone Interactions of Motor Axons with an Intermediate Target. JOURNAL OF NEUROSCIENCE 32:4426-4439(2012).
