CETP
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Official Full Name
cholesteryl ester transfer protein, plasma -
Overview
Cholesteryl ester transfer protein (CETP) transfers cholesteryl esters between lipoproteins. CETP may effect susceptibility to atherosclerosis. -
Synonyms
CETP;cholesteryl ester transfer protein, plasma;cholesteryl ester transfer protein;BPI fold containing family F;BPIFF;CETP_HUMAN;Cholesteryl ester transfer;Cholesteryl ester transfer protein plasma;Cholesteryl ester transfer protein precursor;HDLCQ10;Lipid transfer protein I;OTTHUMP00000164380
Recombinant Proteins
- Human
- Zebrafish
- Chicken
- Rabbit
- E.coli
- Wheat Germ
- Mammalian Cells
- HEK293
- In Vitro Cell Free System
- GST
- His
- DDK
- Myc
- Non
- Flag
- Avi
- Fc
- MBP
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CETP-11131H | Recombinant Human CETP, GST-tagged | E.coli | Human | GST | C-term-350a.a. | |
| CETP-1160H | Recombinant Human CETP Protein, GST-Tagged | Wheat Germ | Human | GST |
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| CETP-1748Z | Recombinant Zebrafish CETP | Mammalian Cells | Zebrafish | His |
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| CETP-19H | Recombinant Human CETP protein, MYC/DDK-tagged | HEK293 | Human | DDK&Myc |
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| CETP-20H | Recombinant Human CETP protein, His-tagged | E.coli | Human | His | Ile81~Ala311 |
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| CETP-21H | Recombinant Human CETP protein, His-tagged | E.coli | Human | His | lys353~Glu443 |
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| CETP-27168TH | Recombinant Human CETP | Wheat Germ | Human | Non | 493 amino acids |
|
| CETP-3272C | Recombinant Chicken CETP | Mammalian Cells | Chicken | His |
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| CETP-7735R | Recombinant Rabbit CETP protein, His-tagged | E.coli | Rabbit | His | His232~His487 |
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| CETP-7559HCL | Recombinant Human CETP 293 Cell Lysate | HEK293 | Human | Non |
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| CETP-1020H | Recombinant Human CETP Protein (Ile81-Ala311), His tagged | E.coli | Human | His | Ile81-Ala311 |
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| CETP-1233HFL | Recombinant Full Length Human CETP Protein, C-Flag-tagged | Mammalian Cells | Human | Flag | Full L. |
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| CETP-3234H | Recombinant Human CETP protein, His-tagged | E.coli | Human | His | Lys353~Gly470 |
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| CETP-3291HF | Recombinant Full Length Human CETP Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 493 amino acids |
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| CETP-581H | Recombinant Human CETP Protein, His (Fc)-Avi-tagged | HEK293 | Human | Avi&Fc&His |
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| CETP-581H-B | Recombinant Human CETP Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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| CETP-72HF | Recombinant Full Length Human CETP Protein | In Vitro Cell Free System | Human | Full L. 493 amino acids |
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| CETP-7547H | Recombinant Human CETP protein, MBP&His-tagged | E.coli | Human | His&MBP | 18-493a.a. |
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| Kit-0208 | CETP Activity Assay Kit | Non |
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| Kit-0209 | CETP Activity Fluorometric Assay Kit II | Non |
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Involved Pathway
CETP involved in several pathways and played different roles in them. We selected most pathways CETP participated on our site, such as HDL-mediated lipid transport,LDL-mediated lipid transport,Lipid digestion, mobilization, and transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with CETP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Statin Pathway | APOC1,APOC4,PDIA2 |
| HDL-mediated lipid transport | APOC2,Alb,AMN,BMP1A,APOA1B,ABCA1 |
| LDL-mediated lipid transport | APOBB.1,APOF,LPA |
| Metabolism of lipids and lipoproteins | CYP4F11,MED23,ACSF3,SACM1LA,DPEP1,GRHL1,CSNK1G2,ARSK,APOBB.1,NEU4 |
| Metabolism | CYP2K22,GLYAT,PNP5B,BCKDK,SLC25A16,UPP2,PROZA,PTGR1,ELA2,PIK3R6 |
| Lipid digestion, mobilization, and transport | APOF,APOBB.1,FABP11B,APOA4B.2,FABP9,LMF1,APOA1B,CLPS,APOA4A,LPA |
| Lipoprotein metabolism | APOA5,APOF,APOA4A,APOA1B,APOA4B.2,APOC2,ABCA1,APOBB.1,APOEA,MTP |
Protein Function
CETP has several biochemical functions, for example, cholesterol binding,cholesterol transporter activity,lipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CETP itself. We selected most functions CETP had, and list some proteins which have the same functions with CETP. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| lipid transporter activity | APOE,VTG1,MTP,SLCO2A1,GM2A,APOD,RFT1,VTG7,VTG2,MTTP |
| cholesterol binding | APOA4,SCP2,NPC2,APOE,SYP,NR1H3,PTCH1,APOD,SOAT1,STARD6 |
| phospholipid transporter activity | ABCA13,ABCA4,ABCA7,GLTPD1,MFSD2AA,ABCA1B,OSBPL5,APOA1,ATP8B5,ABCG1 |
| triglyceride binding | LPL |
| lipid binding | TRIP10,MARK2,SEC14L3,APOA4A,SH3GL2,TRIP10A,FABP12,DNM1L,PITPNM2,APOA1A |
| cholesterol transporter activity | APOA5,ABCG4B,STAR,ABCA13,ABCA7,APOEB,APOE,APOA4B.2,APOA4B.1,APOEA |
| phosphatidylcholine binding | APOA4B.2,SERPINA5,PCTP,GPR12,RPE65,APOA4B.1,APOA1,APOA2,GPR119,RASGRP1 |
Interacting Protein
CETP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CETP here. Most of them are supplied by our site. Hope this information will be useful for your research of CETP.
ARPC3;PRKACG;EWSR1
Resources
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References
- Morton, RE; Izem, L; et al. Modification of CETP function by changing its substrate preference: a new paradigm for CETP drug design. JOURNAL OF LIPID RESEARCH 56:612-619(2015).
- George, M; Selvarajan, S; et al. Looking into the Crystal Ball-Upcoming Drugs for Dyslipidemia. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS 20:11-20(2015).
