CERKL
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Official Full Name
ceramide kinase-like -
Overview
This gene was initially identified as a locus (RP26) associated with an autosomal recessive form of retinitis pigmentosa (arRP) disease. This gene encodes a protein with ceramide kinase-like domains, however, the protein does not phosphorylate ceramide and its target substrate is currently unknown. This protein may be a negative regulator of apoptosis in photoreceptor cells. Mutations in this gene cause a form of retinitis pigmentosa characterized by autosomal recessive cone and rod dystrophy (arCRD). Alternative splicing of this gene results in multiple transcript variants encoding different isoforms and non-coding transcripts. -
Synonyms
CERKL;ceramide kinase-like
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CERKL-5580Z | Recombinant Zebrafish CERKL | Mammalian Cell | Zebrafish | His |
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| CERKL-7566HCL | Recombinant Human CERKL 293 Cell Lysate | HEK293 | Human | Non |
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| CERKL-1547H | Recombinant Human CERKL Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| Cerkl-2120M | Recombinant Mouse Cerkl Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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Involved Pathway
CERKL involved in several pathways and played different roles in them. We selected most pathways CERKL participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CERKL were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
CERKL has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by CERKL itself. We selected most functions CERKL had, and list some proteins which have the same functions with CERKL. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
CERKL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CERKL here. Most of them are supplied by our site. Hope this information will be useful for your research of CERKL.
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