CENPQ
-
Official Full Name
centromere protein Q -
Overview
CENPQ is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM;117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al., 2006;(PubMed 16622420)). -
Synonyms
CENPQ;centromere protein Q;C6orf139, chromosome 6 open reading frame 139;CENP Q;FLJ10545;CENP-Q;CENPQ_HUMAN;OTTHUMP00000016579;C6orf139
Recombinant Proteins
- Human
- Rat
- Mouse
- Chicken
- Cynomolgus
- E.coli
- Wheat Germ
- Mammalian Cell
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- His&Fc&Avi
Involved Pathway
CENPQ involved in several pathways and played different roles in them. We selected most pathways CENPQ participated on our site, such as Cell Cycle,Cell Cycle, Mitotic,Chromosome Maintenance, which may be useful for your reference. Also, other proteins which involved in the same pathway with CENPQ were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Mitotic Metaphase and Anaphase | SKA2,NDEL1A,CENPI,SGOL1,PANE1,PDS5A,CENPH,DSN1,AHCTF1,ERCC6L |
| Mitotic Anaphase | MIS12,ZWILCH,WAPAL,KNTC1,CCDC99,SKA2,PDS5A,PANE1,CENPE,CENPO |
| Chromosome Maintenance | CENPK,ITGB3BP,CENPI,RBBP7,CENPP,CENPW,CENPH,POT1,POLD3,PANE1 |
| Mitotic Prometaphase | AHCTF1,NCAPH,NUDC,INCENP,CENPP,NDEL1,CENPL,MIS12,SKA2,CDCA8 |
| Cell Cycle, Mitotic | E2F4,ENSAA,SETA,CDKN1B,NIPBLB,CDCA5,CENPK,CTDNEP1,RCC2,NUDC |
| Deposition of new CENPA-containing nucleosomes at the centromere | CENPO,CENPI,CENPK,HJURP,CENPW,CENPL,RBBP4,CENPC1,SMARCA5,CENPH |
| Cell cycle | CNEP1R1,STAG2,CDC14AB,ESPL1,ENSAA,RAD9,CEP76,POT1,ORC2L,EP300 |
| M Phase | KIF2B,CLIP1,CENPL,KNTC1,PANE1,CENPP,PDS5B,CENPK,NIPBLA,NCAPG2 |
Protein Function
CENPQ has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by CENPQ itself. We selected most functions CENPQ had, and list some proteins which have the same functions with CENPQ. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
CENPQ has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CENPQ here. Most of them are supplied by our site. Hope this information will be useful for your research of CENPQ.
C19orf57;KDM1A;STRA13;ZFX;RPL9P7;SEC24C;RPS16;RPS14;RPS11;HIST2H4B;RPL10A;CENPC;RPL18;ITGB3BP;TSR1;HIST2H3PS2;CDC42BPA;CENPP;CENPU
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