CENPF
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Official Full Name
centromere protein F, 350/400kDa (mitosin) -
Overview
This gene encodes a protein that associates with the centromere-kinetochore complex. The protein is a component of the nuclear matrix during the G2 phase of interphase. In late G2 the protein associates with the kinetochore and maintains this association through early anaphase. It localizes to the spindle midzone and the intracellular bridge in late anaphase and telophase, respectively, and is thought to be subsequently degraded. The localization of this protein suggests that it may play a role in chromosome segregation during mitotis. It is thought to form either a homodimer or heterodimer. Autoantibodies against this protein have been found in patients with cancer or graft versus host disease. -
Synonyms
CENPF;centromere protein F, 350/400kDa (mitosin);centromere protein F (350/400kD, mitosin);centromere protein F;hcp 1;mitosin;AH antigen;kinetochore protein CENPF;CENP-F kinetochore protein;cell-cycle-dependent 350K nuclear protein;centromere pr
Recombinant Proteins
- Human
- Chicken
- E.coli
- Wheat Germ
- Mammalian Cells
- Insect Cells
- His
- GST
- His&MBP
- His&Myc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CENPF-3311H | Recombinant Human CENPF protein, His-tagged | E.coli | Human | His | 3011-3210 aa | |
| CENPF-1115H | Recombinant Human CENPF Protein, GST-Tagged | Wheat Germ | Human | GST |
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| CENPF-486H | Recombinant Human CENPF Protein, His-tagged | E.coli | Human | His | Gln436~Lys637 |
|
| CENPF-6213C | Recombinant Chicken CENPF | Mammalian Cells | Chicken | His |
|
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| CENPF-011H | Recombinant Human centromere protein F Protein, His tagged | E.coli | Human | His | 2825-3114aa |
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| CENPF-2209H | Recombinant Human CENPF protein, MBP&His-tagged | Insect Cells | Human | His&MBP | 1759-2093aa |
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| CENPF-2743H | Recombinant Human CENPF Protein (1759-2093 aa), His-MBP-tagged | Insect Cells | Human | His&Myc | 1759-2093 aa |
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Involved Pathway
CENPF involved in several pathways and played different roles in them. We selected most pathways CENPF participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CENPF were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
CENPF has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by CENPF itself. We selected most functions CENPF had, and list some proteins which have the same functions with CENPF. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
CENPF has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CENPF here. Most of them are supplied by our site. Hope this information will be useful for your research of CENPF.
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