CELF2
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Official Full Name
CUGBP, Elav-like family member 2 -
Overview
Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Alternative splicing results in multiple transcript variants encoding different isoforms. -
Synonyms
CELF2;CUGBP, Elav-like family member 2;CUG triplet repeat, RNA binding protein 2 , CUG triplet repeat, RNA binding protein 2 , CUGBP2;CUGBP Elav-like family member 2;BRUNOL3;Etr 3;NAPOR 2;Bruno-like protein 3;Cardiac elav type RNA binding protein;CELF-2;CELF2_HUMAN;CUG BP2;CUG triplet repeat RNA-binding protein 2;CUG-BP- and ETR-3-like factor 2;CUG-BP2;dJ323N1.1;elav type RNA binding protein;ELAV-type RNA-binding protein 3;ETR-3;HGNC:2550;hNAPOR;NAPOR;Neuroblastoma apoptosis-related RNA-binding protein;Neuroplastoma apoptosis related RNA binding protein 3;RNA binding protein BRUNOL3;RNA-binding protein BRUNOL-3;OTTHUMP00000019076;OTTHUMP00000019077;OTTHUMP00000019078;CUG triplet repeat, RNA binding protein 2;ETR3;CUGBP2
Recombinant Proteins
- Rat
- Human
- Mouse
- Chicken
- Zebrafish
- Mammalian Cell
- Wheat Germ
- HEK293T
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
CELF2 involved in several pathways and played different roles in them. We selected most pathways CELF2 participated on our site, such as mRNA processing, which may be useful for your reference. Also, other proteins which involved in the same pathway with CELF2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| mRNA processing | WBP4,PRPF4BB,DHX15,SF3A3,HNRNPH1,SF3B2,HNRNPD,D19BWG1357E,DDX39,SFPQ |
Protein Function
CELF2 has several biochemical functions, for example, RNA binding,nucleotide binding,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CELF2 itself. We selected most functions CELF2 had, and list some proteins which have the same functions with CELF2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| poly(A) RNA binding | PNPT1,LARP1,MTERF,RPS14,HIST1H4B,MRPL20,MAGOHB,CDK5R2,PURA,GFM1 |
| RNA binding | RANBP2,IFIT5,SRSF3,ETF1,RPL13,DPPA5A,PCBP2,TARDBP,UPF3A,DUSP11 |
| nucleotide binding | HNRNPA1A,ATP1A1A.4,DNM1A,FLJ11011L,UBE2G1A,RHOGC,EIF4B,SF3B6,NT5C3B,CRY1 |
Interacting Protein
CELF2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CELF2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CELF2.
GRB2;PCBP1;ribF;ssrna_cg;PTBP3;FN1
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