Cdk5rap1
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Official Full Name
CDK5RAP1 CDK5 regulatory subunit associated protein 1 [ Homo sapiens ] -
Overview
This gene encodes a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Tetraspanins are cell surface glycoproteins with four transmembrane domains that form multimeric complexes with other cell surface proteins. The encoded protein functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression of this gene plays a critical role in the suppression of cancer cell motility and metastasis. -
Synonyms
2310066P17Rik;C20orf34;C42;CDK5 activator binding protein C42;CDK5 activator binding protein C42 like;CDK5 regulatory subunit associated protein 1;CDK5RAP1.3;CDK5RAP1.4;CGI 05;HSPC167;OTTMUSP00000016976;RP23-154J12.6;RP5-1187J4.1
Recombinant Proteins
- Human
- Rat
- E.coli
- Wheat Germ
- Mammalian Cells
- HEK293
- In Vitro Cell Free System
- GST
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CDK5RAP1-11052H | Recombinant Human CDK5RAP1, GST-tagged | E.coli | Human | GST | 239-587a.a. | |
| CDK5RAP1-1025H | Recombinant Human CDK5RAP1 Protein, GST-Tagged | Wheat Germ | Human | GST |
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| CDK5RAP1-1307R | Recombinant Rat CDK5RAP1 Protein | Mammalian Cells | Rat | His |
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| CDK5RAP1-7624HCL | Recombinant Human CDK5RAP1 293 Cell Lysate | HEK293 | Human | Non |
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| CDK5RAP1-3127HF | Recombinant Full Length Human CDK5RAP1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 587 amino acids |
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| CDK5RAP1-3138H | Recombinant Human CDK5RAP1 Protein, His-tagged | E.coli | Human | His |
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| CDK5RAP1-965R | Recombinant Rat CDK5RAP1 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| CDK5RAP1-965R-B | Recombinant Rat CDK5RAP1 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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Involved Pathway
Cdk5rap1 involved in several pathways and played different roles in them. We selected most pathways Cdk5rap1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with Cdk5rap1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
Cdk5rap1 has several biochemical functions, for example, NOT 4 iron, 4 sulfur cluster binding,metal ion binding,NOT methylthiotransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Cdk5rap1 itself. We selected most functions Cdk5rap1 had, and list some proteins which have the same functions with Cdk5rap1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein kinase binding | BCL2L14,SUFU,ATP1A1,CDK5R1,CDC42,NCS1,CEP68,CALM3,ZFP36,STXBP1 |
| protein complex binding | MYC,TUB,CEBPA,KHDRBS1,COG2,NSF,TXN2,ST13,ATM,AKAP5 |
| protein kinase regulator activity | KIDINS220B,APC,KIDINS220,RAC2,FAF1,CSNK2B,CDC37,ANKRD54 |
| metal ion binding | CYP8B1,IRGF4,POLK,ASNA1,AMY2B,FREM1,GLIS2B,OVOL2,TIMP2,APLF |
Interacting Protein
Cdk5rap1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Cdk5rap1 here. Most of them are supplied by our site. Hope this information will be useful for your research of Cdk5rap1.
EXOSC5;EXOSC3
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References
- Xie, P; Wei, FY; et al. Quantitative PCR Measurement of tRNA 2-Methylthio Modification for Assessing Type 2 Diabetes Risk. CLINICAL CHEMISTRY 59:1604-1612(2013).
- Brambillasca, S; Altkrueger, A; et al. CDK5 Regulatory Subunit-associated Protein 1-Like 1 (CDKAL1) Is a Tail-anchored Protein in the Endoplasmic Reticulum (ER) of Insulinoma Cells. JOURNAL OF BIOLOGICAL CHEMISTRY 287:41808-41819(2012).
