CDK5R2
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Official Full Name
cyclin-dependent kinase 5, regulatory subunit 2 (p39) -
Overview
Cyclin-dependent kinases (CDKs) are serine/threonine kinases that are activated by cyclins and govern eukaryotic cell cycle progression. While CDK5 shares high sequence homology with its family members, it is thought mainly to function in postmitotic neur -
Synonyms
CDK5R2;cyclin-dependent kinase 5, regulatory subunit 2 (p39);cyclin-dependent kinase 5 activator 2;NCK5AI;neuronal CDK5 activator isoform;P39;p39nck5ai;p39I;CDK5 activator 2;cyclin-dependent kinase 5 regulatory subunit 2;cyclin-dependent kinase
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CDK5R2-1024H | Recombinant Human CDK5R2 Protein, GST-Tagged | Wheat Germ | Human | GST |
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| CDK5R2-3206M | Recombinant Mouse CDK5R2 Protein | Mammalian Cells | Mouse | His |
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| CDK5R2-328HCL | Recombinant Human CDK5R2 cell lysate | Human | Non |
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| CDK5R2-1528M | Recombinant Mouse CDK5R2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| CDK5R2-1528M-B | Recombinant Mouse CDK5R2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| CDK5R2-3126HF | Recombinant Full Length Human CDK5R2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 367 amino acids |
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Involved Pathway
CDK5R2 involved in several pathways and played different roles in them. We selected most pathways CDK5R2 participated on our site, such as Fanconi anemia pathway,Homologous recombination, which may be useful for your reference. Also, other proteins which involved in the same pathway with CDK5R2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Fanconi Anemia Pathway | HES1,EME2,POLN,RPA1,FANCD2,USP36,POLI,RAD51,HER6,TELO2 |
| Homologous recombination | POLD2,RPA2,BRCA2,RPA1,RAD51B,RAD51D,BLM,RPA3,MUS81,POLD4 |
Protein Function
CDK5R2 has several biochemical functions, for example, DNA binding,DNA topoisomerase activity,DNA topoisomerase type I activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CDK5R2 itself. We selected most functions CDK5R2 had, and list some proteins which have the same functions with CDK5R2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| DNA binding | ZNF23,MIER3,TSNAX,TRERF1,E4F1,NFYA,TLR8,ZBTB5,HER13,HIST1H2BO |
| DNA topoisomerase activity | TOP3B |
| protein binding | NID2,PSMA7,SAMD4A,ATP6V1B2,EWSR1A,TBX1,SERPINA5,CAMLG,PLAA,SSX2IP |
| DNA topoisomerase type I activity | TOP1L,TOP1MT,TOP3A,TOP1,TOP3B |
| poly(A) RNA binding | DHX16,PCBP2,D19BWG1357E,RBM12B2,MAP4,MRPS5,MRPL27,TXN,SUPV3L1,H1FX |
Interacting Protein
CDK5R2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDK5R2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDK5R2.
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