CDH8
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Official Full Name
cadherin 8, type 2 -
Overview
This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the proteins homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed in brain and is putatively involved in synaptic adhesion, axon outgrowth and guidance. -
Synonyms
CDH8;cadherin 8, type 2;cadherin-8;Nbla04261
Recombinant Proteins
- Human
- Rat
- Chicken
- Rhesus macaque
- Mouse
- Mus musculus
- HEK293
- Mammalian cells
- Wheat Germ
- Human Cell
- Mammalian Cell
- In Vitro Cell Free System
- HEK293T
- E.coli expression system
- His
- Fc
- GST
- Non
- His&Fc
- His&Fc&Avi
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CDH8-602H | Recombinant Human CDH8 protein, His-tagged | HEK293 | Human | His | Met1-Met621 | |
| CDH8-160H |
Active Recombinant Human CDH8, Fc Chimera
|
Mammalian cells | Human | Fc |
|
|
| CDH8-0995H | Recombinant Human CDH8 Protein, GST-Tagged | Wheat Germ | Human | GST |
|
|
| Cdh8-24R | Recombinant Rat Cdh8, LEVLFQ tagged | Human Cell | Rat | Fc | 1-621 a.a. |
|
| CDH8-26742TH | Recombinant Human CDH8 | Wheat Germ | Human | Non | 100 amino acids |
|
| CDH8-3730C | Recombinant Chicken CDH8 | Mammalian Cell | Chicken | His |
|
|
| CDH8-625H | Recombinant Human CDH8 | Mammalian Cell | Human | His |
|
|
| CDH8-777R | Recombinant Rhesus monkey CDH8 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
|
|
| Cdh8-8760R | Recombinant Rat Cdh8, His tagged | Human Cell | Rat | His&Fc | 1-621 a.a. |
|
| CDH8-2738HCL | Recombinant Human CDH8 cell lysate | Human Cell | Human | Non |
|
|
| CDH8-991RCL | Recombinant Rat CDH8 cell lysate | Human Cell | Rat | Non |
|
|
| CDH8-0271H | Recombinant Human CDH8 Protein (Ala30-Met621), C-His-tagged | Mammalian cells | Human | His | Ala30-Met621 |
|
| CDH8-1039R | Recombinant Rat CDH8 protein(Met1-Met621) | HEK293 | Rat | Non | Met1-Met621 |
|
| CDH8-178H | Recombinant Human CDH8 Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
|
|
| CDH8-178H-B | Recombinant Human CDH8 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
|
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| CDH8-3148H | Recombinant Human CDH8 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
|
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| CDH8-3152HF | Recombinant Full Length Human CDH8 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 799 amino acids |
|
| CDH8-3373R | Recombinant Rat CDH8 protein(Met1-Met621), His-tagged | HEK293 | Rat | His | Met1-Met621 |
|
| CDH8-4940H | Recombinant Human CDH8 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
|
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| CDH8-603R | Recombinant Rhesus Macaque CDH8 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
|
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| CDH8-603R-B | Recombinant Rhesus Macaque CDH8 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
|
||
| Cdh8-863M | Recombinant Mouse Cdh8 Protein, MYC/DDK-tagged | HEK293T | Mouse | Myc&DDK |
|
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| RFL18244MF | Recombinant Full Length Mouse Cadherin-8(Cdh8) Protein, His-Tagged | E.coli expression system | Mus musculus | His | Full L. Full Length of Mature Protein (62-799) |
|
| RFL26641HF | Recombinant Full Length Human Cadherin-8(Cdh8) Protein, His-Tagged | E.coli expression system | Human | His | Full L. Full Length of Mature Protein (62-799) |
|
| RFL26735RF | Recombinant Full Length Rat Cadherin-8(Cdh8) Protein, His-Tagged | E.coli expression system | Rat | His | Full L. Full Length of Mature Protein (62-799) |
|
Involved Pathway
CDH8 involved in several pathways and played different roles in them. We selected most pathways CDH8 participated on our site, such as Adherens junctions interactions,Cell junction organization,Cell-Cell communication, which may be useful for your reference. Also, other proteins which involved in the same pathway with CDH8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cell-cell junction organization | PVRL2L,CLDN16,CLDN23,CDH24,CDH17,CDH7,CLDN4,CTNND1,CDH11,CDH18A |
| Cell junction organization | ANG,CLDN3,CLDN16,FBLIM1,CDH17,CLDN4,JUP,COL17A1A,CDH6,CDH18 |
| Adherens junctions interactions | PTBP3,CDH10,CTNND1,CDH13,CDH24,CADM2A,CDH4,CDH17,JUPA,CDH3 |
| Cell-Cell communication | CADM2A,PVRL2L,JUP,CLDN4,KIRREL3L,COL17A1A,KIRREL3,CLDN23,CDH3,DCC |
Protein Function
CDH8 has several biochemical functions, for example, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CDH8 itself. We selected most functions CDH8 had, and list some proteins which have the same functions with CDH8. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| calcium ion binding | NCALDA,CANT1A,DGKAA,PKD1L3,SNCB,MYLPF,ANXA5A,CRELD2,MASP1,FBN1 |
Interacting Protein
CDH8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDH8 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDH8.
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