CDC42EP5
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Official Full Name
CDC42 effector protein (Rho GTPase binding) 5 -
Overview
CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. The specific function of this protein has not yet been determined. -
Synonyms
CDC42EP5;CDC42 effector protein (Rho GTPase binding) 5;Borg3;CEP5;1700027J19Rik;2010007O02Rik
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CDC42EP5-3147M | Recombinant Mouse CDC42EP5 Protein | Mammalian Cells | Mouse | His |
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| CDC42EP5-1490M | Recombinant Mouse CDC42EP5 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| CDC42EP5-1490M-B | Recombinant Mouse CDC42EP5 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
CDC42EP5 involved in several pathways and played different roles in them. We selected most pathways CDC42EP5 participated on our site, such as MAPK family signaling cascades,MAPK6/MAPK4 signaling,Signal Transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with CDC42EP5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| MAPK6/MAPK4 signaling | CDC42EP3,MAPK6,MAPK4,CDC42EP1B,CDC42EP2,SEPT7,IGF2BP1 |
| XPodNet - protein-protein interactions in the podocyte expanded by STRING | WLS,RAVER1,Siglece,Ighg,MTAP1A,ARHGAP33,PKD1,TENC1,DDN,CMIP |
| MAPK family signaling cascades | MAPK6,MAPK4,SEPT7,IGF2BP1,CDC42EP2,CDC42EP3,CDC42EP1B |
| Signal Transduction | CCL35.1,SOX4A,SKI,OPN1LW1,PROKR1,SST1.1,CBY1,ANXA1B,EMR3,RAMP1 |
Protein Function
CDC42EP5 has several biochemical functions, for example, GTP-Rho binding,GTPase activator activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CDC42EP5 itself. We selected most functions CDC42EP5 had, and list some proteins which have the same functions with CDC42EP5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GTPase activator activity | GIT1,TBCD,ARHGAP11A,SMAP2,ARHGEF15,GRTP1,ARHGAP27,ARHGAP42,TBC1D8B,ARFGAP3 |
| GTP-Rho binding | STXBP6,ROCK2A,CDC42EP4,TNFAIP1,CDC42EP2,RTKN2B,EXOC1,STXBP6L,CDC42EP4A,TRIOBP |
| protein binding | NFYB,LMO2,EXOSC1,IL6,TRAPPC2L,NIF3L1,ETV5,ANKRD27,CCDC135,SMAD3B |
Interacting Protein
CDC42EP5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDC42EP5 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDC42EP5.
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