CDC2L6
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Official Full Name
CDK19 cyclin-dependent kinase 19 -
Overview
This gene encodes a protein that is one of the components of the Mediator coactivator complex. The Mediator complex is a multiprotein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II. The protein encoded by this gene is similar to cyclin-dependent kinase 8 which can also be a component of the Mediator complex. -
Synonyms
CDK11;CDC2L6;KIAA1028;bA346C16.3;cyclin-dependent kinase 19;OTTHUMP00000017005;OTTHUMP00000017006;OTTHUMP00000017007;death-preventing kinase;cyclin-dependent kinase 11;CDC2-related protein kinase 6;cell division protein kinase 19;CDK8-like cyclin-dependent kinase;cyclin-dependent kinase (CDC2-like) 11;cell division cycle 2-like 6 (CDK8-like);cell division cycle 2-like protein kinase 6
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CDC2L6-11004H | Recombinant Human CDC2L6, GST-tagged | E.coli | Human | GST | 1-335a.a. | |
| CDC2L6-3293H | Recombinant Human CDC2L6 protein, His-tagged | E.coli | Human | His | 1-335 aa |
Involved Pathway
CDC2L6 involved in several pathways and played different roles in them. We selected most pathways CDC2L6 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CDC2L6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
CDC2L6 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by CDC2L6 itself. We selected most functions CDC2L6 had, and list some proteins which have the same functions with CDC2L6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
CDC2L6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDC2L6 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDC2L6.
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References
- Lotan, Y; Bagrodia, A; et al. Prospective Evaluation of a Molecular Marker Panel for Prediction of Recurrence and Cancer-specific Survival After Radical Cystectomy. EUROPEAN UROLOGY 64:465-471(2013).
- Kuo, CN; Chen, CY; et al. Cell cycle regulation by bevacizumab in ARPE-19 human retinal pigment epithelial cells. MOLECULAR MEDICINE REPORTS 6:701-704(2012).
