CDC2
-
Official Full Name
CDK1 cyclin-dependent kinase 1 -
Overview
The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. -
Synonyms
CDC2;CDC28A;P34CDC2;MGC111195;DKFZp686L20222;cyclin-dependent kinase 1;OTTHUMP00000019659;OTTHUMP00000019660;OTTHUMP00000223862;p34 protein kinase;cell cycle controller CDC2;cell division protein kinase 1;cell division control protein 2 homolog;cell division cycle 2, G1 to S and G2 to M
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CDC2-0904H | Recombinant Human CDC2 Protein, GST-Tagged | Wheat Germ | Human | GST |
|
|
| CDC2-0906H | Recombinant Human CDC2 protein(Met1-Met297), GST-tagged | Insect Cells | Human | GST | Met1-Met297 |
|
| CDC2-0907H | Active Recombinant Human CDC2 Protein, GST-His-Tagged | Insect Cells | Human | His&GST | 1-297;1-433 a.a. |
|
| CDC2-3176HF | Recombinant Full Length Human CDC2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 297 amino acids |
|
Involved Pathway
CDC2 involved in several pathways and played different roles in them. We selected most pathways CDC2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CDC2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
CDC2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by CDC2 itself. We selected most functions CDC2 had, and list some proteins which have the same functions with CDC2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
CDC2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDC2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDC2.
CDC2 Related Signal Pathway
Resources
Related Services
Related Products
References
- Talakhun, W; Phaonakrop, N; et al. Proteomic analysis of ovarian proteins and characterization of thymosin-beta and RAC-GTPase activating protein 1 of the giant tiger shrimp Penaeus monodon. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY D-GENOMICS & PROTEOMICS 11:9-19(2014).
- Tian, H; Guo, MJ; et al. Enhanced proliferation of bone marrow mesenchymal stem cells by co-culture with TM4 mouse Sertoli cells: involvement of the EGF/PI3K/AKT pathway. MOLECULAR AND CELLULAR BIOCHEMISTRY 393:155-164(2014).
