CDC16
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Official Full Name
cell division cycle 16 homolog (S. cerevisiae) -
Overview
This gene encodes a component protein of the APC complex, which is composed of eight proteins and functions as a protein ubiquitin ligase. The APC complex is a cyclin degradation system that governs exit from mitosis. Each component protein of the APC complex is highly conserved among eukaryotic organisms. This protein and two other APC complex proteins, CDC23 and CDC27, contain a tetratricopeptide repeat (TPR), a protein domain that may be involved in protein-protein interaction. Multiple alternatively spliced variants, encoding the same protein, have been identified. -
Synonyms
CDC16;cell division cycle 16 homolog (S. cerevisiae);CDC16 (cell division cycle 16, S. cerevisiae, homolog) , CDC16 cell division cycle 16 homolog (S. cerevisiae);cell division cycle protein 16 homolog;ANAPC6;anaphase promoting complex;subunit 6;APC6;CUT9;Anaphase promoting complex subunit 6;Anaphase-promoting complex subunit 6;Apc 6;CDC 16;CDC16 (cell division cycle 16 S. cerevisiae homolog);CDC16 homolog;CDC16 protein;CDC16_HUMAN;CDC16Hs;Cell division cycle 16 homolog;Cyclosome subunit 6;anaphase-promoting complex, subunit 6
Recombinant Proteins
- Human
- Chicken
- Zebrafish
- Rhesus macaque
- Mouse
- Wheat Germ
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- In Vitro Cell Free System
- GST
- His&T7
- His
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
CDC16 involved in several pathways and played different roles in them. We selected most pathways CDC16 participated on our site, such as Cell cycle,Oocyte meiosis,Ubiquitin mediated proteolysis, which may be useful for your reference. Also, other proteins which involved in the same pathway with CDC16 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Oocyte meiosis | FBXO5,SPDYA,MOS,REC8B,CPEB1B,SGOL1,CALM2,PPP3CCA,PLCZ1,CALM3B |
| HTLV-I infection | IKBKG,GM-CSF,APC,HLA-DOA,NFATC2,SLC25A5,VDAC1,POLE,HLA-DOB,WNT4 |
| Cell cycle | KAT5,ORC6,EP300,GINS3,LIN9,NIPBL,DNA2,BUB1B,SPDL1,SMAD3 |
| Ubiquitin mediated proteolysis | CUL2,UBE2Q2,UBE2Q1,UBE2G1A,UBOX5,CUL1B,UBE2H,TRIM32,ITCH,PARK2 |
| Progesterone-mediated oocyte maturation | Adcy4,MAPK1,RAF1,GNAI3,CCNA1,PRKACG,CDK1,AKT3A,RPS6KA1,PKMYT1 |
Protein Function
CDC16 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CDC16 itself. We selected most functions CDC16 had, and list some proteins which have the same functions with CDC16. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | GLI1,CDX4,SMAP2,CHMP4A,URM1,IL11,WDR18,TAC3,NCLN,GSS |
Interacting Protein
CDC16 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDC16 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDC16.
CDC26;CDC27;CDC20;ANAPC1
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References
- Luo, Y; Sarabi, SA; et al. Expression pattern of NuIP gene in adult mouse brain. BRAIN RESEARCH 1302:42-53(2009).
- Imai, A; Yoshie, S; et al. EPI64 Protein Functions as a Physiological GTPase-activating Protein for Rab27 Protein and Regulates Amylase Release in Rat Parotid Acinar Cells. JOURNAL OF BIOLOGICAL CHEMISTRY 286:33854-33862(2011).
