CCAR1
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Official Full Name
cell division cycle and apoptosis regulator 1 -
Overview
Cell division cycle and apoptosis regulator protein 1 is a protein that in humans is encoded by the CCAR1 gene. -
Synonyms
CCAR1;cell division cycle and apoptosis regulator 1;cell division cycle and apoptosis regulator protein 1;CARP 1;CARP1;FLJ10590;death inducer with SAP domain;cell cycle and apoptosis regulatory protein 1;MGC44628;RP11-437A18.1
Recombinant Proteins
- Mouse
- Rhesus macaque
- Zebrafish
- Human
- Mammalian Cell
- HEK293
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CCAR1-2802M | Recombinant Mouse CCAR1 Protein | Mammalian Cell | Mouse | His |
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| CCAR1-651R | Recombinant Rhesus monkey CCAR1 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| CCAR1-7346Z | Recombinant Zebrafish CCAR1 | Mammalian Cell | Zebrafish | His |
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| CCAR1-7797HCL | Recombinant Human CCAR1 293 Cell Lysate | HEK293 | Human | Non |
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| CCAR1-1278M | Recombinant Mouse CCAR1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| CCAR1-1278M-B | Recombinant Mouse CCAR1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| CCAR1-479R | Recombinant Rhesus Macaque CCAR1 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| CCAR1-479R-B | Recombinant Rhesus Macaque CCAR1 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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Involved Pathway
CCAR1 involved in several pathways and played different roles in them. We selected most pathways CCAR1 participated on our site, such as Gene Expression,Processing of Capped Intron-Containing Pre-mRNA,mRNA Splicing, which may be useful for your reference. Also, other proteins which involved in the same pathway with CCAR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| mRNA Splicing - Major Pathway | SF3B4,HNRNPF,PCBP2,SF3B2,HNRNPA0L,TXNL4A,PTBP1,HNRNPD,SF3A1,CD2BP2 |
| Gene Expression | ZNF839,POP1,PIWIL4,POLR3C,CDK9,TH1L,CD2BP2,NT5C3B,ZNF18,TXN |
| mRNA Splicing | RBM5,HNRNPR,ZMAT5,RNPC3,PTBP1,DNAJC8,TXNL4A,YBX1,SF3A1,HNRNPD |
| Processing of Capped Intron-Containing Pre-mRNA | HNRNPF,HNRNPH1L,WTAP,RNPC3,HNRNPUL1,METTL3,PRPF8,SUGP1,PTBP1,SLBP |
Protein Function
CCAR1 has several biochemical functions, for example, core promoter binding,ligand-dependent nuclear receptor transcription coactivator activity,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CCAR1 itself. We selected most functions CCAR1 had, and list some proteins which have the same functions with CCAR1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ligand-dependent nuclear receptor transcription coactivator activity | PKN1,USP22,THRAP3,MED1,SMARCD3,WDR77,RBM14,NCOA2,PRKCBB,BUD31 |
| poly(A) RNA binding | YBX1,NCL,SNRPC,RPL31,MRPS35,PPP1R2P9,FAM32A,CHCHD1,LARP4,TFB1M |
| transcription coactivator activity | PML,ESRRB,STIL,MED14,USP22,SMARCA4,CARM1,LPIN3,ENY2,TFAP2A |
| transcription corepressor activity | HSBP1,SIRT6,SMYD1,NRIP1,ARHGAP35,BCL11A,SKI,LDB1,THRB,NR2F2 |
| protein binding | FLG,TLE4,HTR1E,RNF213,NR2C2AP,HSF2,NQO1,PYGM,DERL1,SOCS1 |
| core promoter binding | FOXP3,MED1,KLF4,NKX3,E2F3,CALCOCO1,EP300,NPAS2,NONO,IFI203 |
Interacting Protein
CCAR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CCAR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CCAR1.
GOLGA2;PIH1D3;TRIM63;Wwtr1;Kif23;EEF1D;SF3A2;FYCO1;TRIM55;WWTR1
Resources
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References
- Ramaiah, MJ; Lavanya, A; et al. miR-15/16 complex targets p70S6 kinase1 and controls cell proliferation in MDA-MB-231 breast cancer cells. GENE 552:255-264(2014).
- Ozden, S; Tiber, PM; et al. Expression of TRF2 and its prognostic relevance in advanced stage cervical cancer patients. BIOLOGICAL RESEARCH 47:-(2014).
