CARD18
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Official Full Name
caspase recruitment domain family, member 18 -
Synonyms
CARD18;caspase recruitment domain family, member 18;caspase recruitment domain-containing protein 18;ICEBERG;pseudo ICE;UNQ5804;Caspase 1 inhibitor Iceberg;ICEBERG caspase-1 inhibitor;caspase-1 inhibitor Iceberg;pseudo-ICE
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CARD18-832HCL | Recombinant Human CARD18 cell lysate | Human | Non |
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| CARD18-2525H | Recombinant Human CARD18 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| CARD18-5069H | Recombinant Human CARD18 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | Myc&DDK |
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Involved Pathway
CARD18 involved in several pathways and played different roles in them. We selected most pathways CARD18 participated on our site, such as NOD-like receptor signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CARD18 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| NOD-like receptor signaling pathway | CXCL2,CARD9,CASP5,NFKB1,MAPK13,HSP90AA1,IL-8,PSTPIP1B,NLRP1,NLRP3 |
Protein Function
CARD18 has several biochemical functions, for example, cysteine-type endopeptidase inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CARD18 itself. We selected most functions CARD18 had, and list some proteins which have the same functions with CARD18. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cysteine-type endopeptidase inhibitor activity | CST5,BIRC5A,CST11,AHSG2,NGP,CTLA2B,CSTA,CST9L,NAIP1,CST3 |
Interacting Protein
CARD18 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CARD18 here. Most of them are supplied by our site. Hope this information will be useful for your research of CARD18.
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References
- Prescimone, T; D'Amico, A; et al. Caspase-1 transcripts in failing human heart after mechanical unloading. CARDIOVASCULAR PATHOLOGY 24:11-18(2015).
- Lechtenberg, BC; Mace, PD; et al. Structural mechanisms in NLR inflammasome signaling. CURRENT OPINION IN STRUCTURAL BIOLOGY 29:17-25(2014).
