CACNG2
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Official Full Name
Cacng2 calcium channel, voltage-dependent, gamma subunit 2 -
Synonyms
CACNG2;calcium channel, voltage-dependent, gamma subunit 2;voltage-dependent calcium channel gamma-2 subunit;TARP gamma 2;TARP gamma-2;transmembrane AMPAR regulatory protein gamma-2;neuronal voltage-gated calcium channel gamma-2 subunit;stg;wag;waggler;AW060990;stargazer;stargazin;B230105C07Rik;B930041E13Rik;MGC123981
Recombinant Proteins
- Human
- Mouse
- Mus musculus
- Rat
- E.coli
- Mammalian Cell
- HEK293
- E.coli expression system
- His
- Non
- His&Fc&Avi
Involved Pathway
CACNG2 involved in several pathways and played different roles in them. We selected most pathways CACNG2 participated on our site, such as Adrenergic signaling in cardiomyocytes,Arrhythmogenic right ventricular cardiomyopathy,Arrhythmogenic right ventricular cardiomyopathy (ARVC), which may be useful for your reference. Also, other proteins which involved in the same pathway with CACNG2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Dilated cardiomyopathy | CACNA2D1,SGCD,CACNB4,ITGB8,Itga10&Itgb1,SGCB,TPM4,ITGB4,LMNA,SGCA |
| Arrhythmogenic right ventricular cardiomyopathy | CDH2,CTNNA1,CTNNA2,DES,JUP,CACNG3,DMD,DSC2,DSP,DSG2 |
| Cardiac muscle contraction | TPM3,COX7B2,ACTC1A,COX5B,CACNG1A,ATP1A2,SLC9A1,COX6A1,CACNA1SA,CACNG8 |
| Developmental Biology | AP2B1,RHOAE,ACTR2B,FRS3,EVL,NRG4,CARM1,PSPN,AP2A1,FGF18B |
| Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels | CACNB4B,CACFD1,CACNG2B |
| Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity | MYO6,GRIP1,NSFA,AKAP5,NSFB,PICK1,HAND2,CACNG3 |
| Arrhythmogenic right ventricular cardiomyopathy (ARVC) | LAMA2,ACTN2,CACNB3,ITGA2B,ITGB5,DSC2,ITGA5,CACNA2D3,ACTN4,SGCG |
| Adrenergic signaling in cardiomyocytes | ADCY9,ADRA1BB,ACTC1,BCL2A,ATF4,CACNA2D1,CALM2,CREB3L2,NETO2,KCNE1 |
Protein Function
CACNG2 has several biochemical functions, for example, channel regulator activity,ionotropic glutamate receptor binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CACNG2 itself. We selected most functions CACNG2 had, and list some proteins which have the same functions with CACNG2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ionotropic glutamate receptor binding | SHANK1,GNAS,NETO1,SHANK3,DLG1L,DLG1,DLG4,DRD2,RAB4A,ADRB2 |
| protein binding | RPL10A,ASB3,KLHL7,LITAF,PRPS1,H1F0,cgr2b,C21orf2,CDK20,PCGF3 |
| voltage-gated calcium channel activity | CATSPER3,TPC3,IL1RAPL1,CACNG1,TMC1,CACNA2D4,ATP6V0CB,CACNA1DA,TPCN2,CALHM1 |
| channel regulator activity | CACNG3,CACNG7,CNIH3,SLC9A3R2,SNF8,CACNG4,CACNG7A,CACNG8,CACNG8A,CACNG2B |
Interacting Protein
CACNG2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CACNG2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CACNG2.
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References
- Endoh, T; Sato, D; et al. Galanin inhibits calcium channels via G alpha(i)-protein mediated by GalR1 in rat nucleus tractus solitarius. BRAIN RESEARCH 1229:37-46(2008).
- Endoh, T; et al. Dual effects of neurokinin on calcium channel currents and signal pathways in neonatal rat nucleus tractus solitarius. BRAIN RESEARCH 1110:116-127(2006).
