C8B

  • Official Full Name

    complement component 8, beta polypeptide
  • Overview

    C8 beta is one of the three subunits that comprise the component 8 (C8) of the complement system. C8 participates in the formation of Membrane Attack Complex that results in the lysis of cells. Patients with C8B deficiency are prone to bacteria infection.
  • Synonyms

    C8B;complement component 8, beta polypeptide;complement component C8 beta chain;complement component 8 subunit beta;MGC163447

Recombinant Proteins

  • Rat
  • Human
  • Mouse
  • Zebrafish
  • Mammalian Cell
  • E.coli
  • HEK293
  • Mammalian cells
  • HEK293T
  • His
  • His&T7
  • Non
  • Flag
  • Myc&DDK
  • His&Fc&Avi
  • His&Myc
Cat.# Product name Source (Host) Species Tag Protein Length Price
C8B-1055R Recombinant Rat C8B Protein Mammalian Cell Rat His
C8B-6786H Recombinant Human C8B protein, His & T7-tagged E.coli Human His&T7 Cys162~His504
C8b-6787M Recombinant Mouse C8b protein, His & T7-tagged E.coli Mouse His&T7 Cys161~Arg503
C8b-6788R Recombinant Rat C8b protein, His & T7-tagged E.coli Rat His&T7 Cys161~Arg503
C8B-8192Z Recombinant Zebrafish C8B Mammalian Cell Zebrafish His
C8B-7955HCL Recombinant Human C8B 293 Cell Lysate HEK293 Human Non
C8B-0617H Recombinant Human C8B Protein (Cys162-His504), N-His-tagged E.coli Human His Cys162-His504
C8B-1903HFL Recombinant Full Length Human C8B Protein, C-Flag-tagged Mammalian cells Human Flag Full L.
C8b-469M Recombinant Mouse C8b Protein, MYC/DDK-tagged HEK293T Mouse Myc&DDK
C8B-476H Recombinant Human C8B Protein, His (Fc)-Avi-tagged HEK293 Human His&Fc&Avi
C8B-476H-B Recombinant Human C8B Protein Pre-coupled Magnetic Beads HEK293 Human
C8B-617H Recombinant Human C8B protein, His&Myc-tagged E.coli Human His&Myc 55-591aa
C8B-618H Recombinant Human C8B protein, His-tagged E.coli Human His 55-591aa
C8B-713R Recombinant Rat C8B Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
C8B-713R-B Recombinant Rat C8B Protein Pre-coupled Magnetic Beads HEK293 Rat

    Involved Pathway

    C8B involved in several pathways and played different roles in them. We selected most pathways C8B participated on our site, such as Complement and coagulation cascades,Prion diseases,Amoebiasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with C8B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Prion diseases LOC100033925,C9,PRKACB,LAMC1,BAX,MAP2K1,Hc,C7,C8A,CCL5
    Amoebiasis NOS2,PRKCB,PIK3CA,CD14,IL-8,PRKACB,PIK3R2,CD1d1,GNA15,TLR4
    Systemic lupus erythematosus HIST2H4,HIST1H2AB,HIST1H3D,CD28,CD80,H3F3A,HIST1H2AL,C9,TRIM21,HIST1H3C
    Complement and coagulation cascades C8A,F8,C2,GM5077,PLAU,F3,SERPING1,Hc,CD59,BDKRB2

    Protein Function

    C8B has several biochemical functions, for example, protein complex binding. Some of the functions are cooperated with other proteins, some of the functions could acted by C8B itself. We selected most functions C8B had, and list some proteins which have the same functions with C8B. You can find most of the proteins on our site.

    Function Related Protein
    protein complex binding TELO2,IGBP1,NRAS,SHARPIN,EPCAM,VDAC1,SHANK1,NCK2,PCSK2,TUBB

    Interacting Protein

    C8B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with C8B here. Most of them are supplied by our site. Hope this information will be useful for your research of C8B.

    Resources

    References

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