C7orf16
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Official Full Name
chromosome 7 open reading frame 16 -
Overview
The protein encoded by this gene is found primarily in cerebellar Purkinje cells, where it functions as a protein phosphatase inhibitor. The encoded protein is a substrate for cGMP-dependent protein kinase. An allele of this gene was discovered that increases susceptibility to hypercholesterolemia. Two transcript variants encoding different isoforms have been found for this gene. -
Synonyms
chromosome 7 open reading frame 16;GSBS;G-substrate;OTTHUMP00000158793;OTTHUMP00000202600
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Involved Pathway
C7orf16 involved in several pathways and played different roles in them. We selected most pathways C7orf16 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with C7orf16 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
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Protein Function
C7orf16 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by C7orf16 itself. We selected most functions C7orf16 had, and list some proteins which have the same functions with C7orf16. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
C7orf16 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with C7orf16 here. Most of them are supplied by our site. Hope this information will be useful for your research of C7orf16.
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References
- Iizuka, M; Murata, T; et al. Increased contractility of hepatic stellate cells in cirrhosis is mediated by enhanced Ca2+-dependent and Ca2+-sensitization pathways. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY 300:G1010-G1021(2011).
- Murthy, KS; Zhou, HP; et al. Differential signalling by muscarinic receptors in smooth muscle: m2-mediated inactivation of myosin light chain kinase via G(i3), Cdc42/Rac1 and p21-activated kinase 1 pathway, and m3-mediated MLC20 (20 kDa regulatory light chain of myosin II) phosphorylation via Rho-associated kinase/myosin phosphatase targeting subunit 1 and protein kinase C/CPI-17 pathway. BIOCHEMICAL JOURNAL 374:145-155(2003).
