C19ORF40
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Official Full Name
chromosome 19 open reading frame 40 -
Overview
FAAP24 is a component of the Fanconi anemia (FA) core complex (see MIM 227650), which plays a crucial role in DNA damage response (Ciccia et al., 2007 [PubMed 17289582]).[supplied by OMIM, Mar 2008] -
Synonyms
C19ORF40;chromosome 19 open reading frame 40;FAAP24;Fanconi anemia-associated protein of 24 kDa;Fanconi anemia-associated protein, 24 kDa
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| C19orf40-2742H | Recombinant Human C19orf40 protein, His-tagged | E.coli | Human | His | 1-215 aa | |
| C19orf40-8207HCL | Recombinant Human C19orf40 293 Cell Lysate | HEK293 | Human | Non |
|
Involved Pathway
C19ORF40 involved in several pathways and played different roles in them. We selected most pathways C19ORF40 participated on our site, such as Fanconi anemia pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with C19ORF40 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Fanconi Anemia Pathway | RMI1,ERCC4,RPA4,TOP3A,FANCC,MLH1,POLI,BRCA2,FANCG,STRA13 |
Protein Function
C19ORF40 has several biochemical functions, for example, DNA binding,chromatin binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by C19ORF40 itself. We selected most functions C19ORF40 had, and list some proteins which have the same functions with C19ORF40. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| DNA binding | ZFP382,HOXB9A,SIX1,STAT1A,EBF2,ZNF266,HDGF,ZFP770,THRB,STRA13 |
| chromatin binding | ARID3A,MEF2A,MSGN1,ING5,WDHD1,HMG20B,GATA3,SMARCC1,HDAC3,ASCL1 |
| protein binding | TRIB3,MRM1,NUFIP1,KCTD5,GLP1R,ODC1,HIST1H2BB,TRIM33,SLIRP,RPS27 |
Interacting Protein
C19ORF40 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with C19ORF40 here. Most of them are supplied by our site. Hope this information will be useful for your research of C19ORF40.
LRRK2;TRAF6
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References
- Boeve, BF; Boylan, KB; et al. Characterization of frontotemporal dementia and/or amyotrophic lateral sclerosis associated with the GGGGCC repeat expansion in C9ORF72. BRAIN 135:765-783(2012).
- Fujiwara, A; Kawasaki, T; et al. Genomic characterization of Ralstonia solanacearum phage phi RSA1 and its related prophage (phi RSX) in strain GMI1000. JOURNAL OF BACTERIOLOGY 190:143-156(2008).
