BSND
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Official Full Name
Bartter syndrome, infantile, with sensorineural deafness (Barttin) -
Overview
This gene encodes an essential beta subunit for CLC chloride channels. These heteromeric channels localize to basolateral membranes of renal tubules and of potassium-secreting epithelia of the inner ear. Mutations in this gene have been associated with Bartter syndrome with sensorineural deafness. -
Synonyms
BSND;Bartter syndrome, infantile, with sensorineural deafness (Barttin);deafness, autosomal recessive 73 , DFNB73;barttin;BART;deafness, autosomal recessive 73;DFNB73;MGC119283;MGC119284;MGC119285
Recombinant Proteins
- Human
- Rat
- Mouse
- E.coli
- Mammalian Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- GST
- His
- Non
- His&Fc&Avi
Involved Pathway
BSND involved in several pathways and played different roles in them. We selected most pathways BSND participated on our site, such as Ion channel transport,Stimuli-sensing channels,Transmembrane transport of small molecules, which may be useful for your reference. Also, other proteins which involved in the same pathway with BSND were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ion channel transport | OSTM1,HTR3C,SRI,ASIC1A,ANO7,ANO10A,TRPC4APA,ANO1,TRPV3,CLCN7 |
| Transmembrane transport of small molecules | SLC35B3,ANO5B,CUTC,ATP13A,SLC5A6B,SLC30A3,FXYD7,SLC7A3,TRPM4C,SLC24A6 |
| Stimuli-sensing channels | TRPM1A,TRPC4B,TRPA1B,WNK2,UNC79,CLCNKA,CLCN4,ANO4,BEST3,CLCN6 |
Protein Function
BSND has several biochemical functions, for example, contributes_to chloride channel activity,chloride channel regulator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by BSND itself. We selected most functions BSND had, and list some proteins which have the same functions with BSND. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| chloride channel regulator activity | SGK2,CHRNA7,SGK2A,SGK3,SGK2B,SLC9A3R1,SGK1 |
| contributes_to chloride channel activity | GABRB3,BEST3,GABRB2,BEST4,GABRR2A,GABRQ,GABRR3A,GABRB1,GABRR2,BEST1 |
Interacting Protein
BSND has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BSND here. Most of them are supplied by our site. Hope this information will be useful for your research of BSND.
ARL2;ARL3
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