BRF2
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Official Full Name
BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like -
Overview
This gene encodes one of the multiple subunits of the RNA polymerase III transcription factor complex required for transcription of genes with promoter elements upstream of the initiation site. The product of this gene, a TFIIB-like factor, is directly recruited to the TATA-box of polymerase III small nuclear RNA gene promoters through its interaction with the TATA-binding protein. -
Synonyms
BRF2;BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like;transcription factor IIIB 50 kDa subunit;BRFU;FLJ11052;TFIIIB50;B-related factor 2;BRF-2;BRF2_HUMAN;hBRFU;hTFIIIB50;RNA polymerase III transcription initiation factor BRF2;Transcription factor IIB- related factor TFIIIB50;transcription factor IIB- related factor, TFIIIB50;RNA polymerase III transcription initiation factor BRFU
Recombinant Proteins
- Human
- Rat
- Mouse
- Cynomolgus
- Zebrafish
- E.coli
- Mammalian Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- GST
- His
- Non
- Avi
- Fc
- DDK
- Myc
Involved Pathway
BRF2 involved in several pathways and played different roles in them. We selected most pathways BRF2 participated on our site, such as Gene Expression,RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription,RNA Polymerase III Abortive And Retractive Initiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with BRF2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription | CBX3A,RRN3,SNAPC5,CRCP,BRF1,POLRMT,MBD3,GATAD2B,SNAPC4,POU2F1B |
| RNA Polymerase III Transcription Initiation From Type 3 Promoter | ZNF143,ZNF143A,SNAPC3,SNAPC1,SNAPC2,SNAPC5,SNAPC1B,ZNF143B,ZFP143,POU2F1B |
| Gene Expression | Txn1,SF3A3,DCP1B,TP53RK,MED7,ZNF583,TFB2M,ZNF263,ZNF567,ZNF471 |
| RNA Polymerase III Transcription Initiation | SNAPC1A,GTF3C3,GTF3AA,SNAPC4,ZFP143,SNAPC3,POLR3GLA,BRF1B,ZNF143A,SNAPC1 |
| RNA Polymerase III Abortive And Retractive Initiation | SNAPC1,POU2F1,NFIC,GTF3C4,NFIB,GTF3C3,NFIX,GTF3C2,SNAPC3,SNAPC2 |
| RNA Polymerase III Transcription | BRF1B,GTF3A,NFIC,SNAPC1A,POU2F1B,SNAPC3,GTF3C4,GTF3AB,ZNF143A,SNAPC1B |
Protein Function
BRF2 has several biochemical functions, for example, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BRF2 itself. We selected most functions BRF2 had, and list some proteins which have the same functions with BRF2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| zinc ion binding | CPA1,MAN2A1,ZFYVE1,CHORDC1,MARCH6,TADA2B,KDM4B,ING4,LIMK1,NR5A1A |
Interacting Protein
BRF2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BRF2 here. Most of them are supplied by our site. Hope this information will be useful for your research of BRF2.
TIMM23;SURF4;PSMD3;ZW10;MYO1B;DPM1;SF3B1;AIFM1;HSPB1;SLC3A2;PDHB;TBP;KDELR1;ABCD3;MCM7;COPB2;ARL1
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References
- Reznik, B; Clement, SL; et al. hnRNP F Complexes with Tristetraprolin and Stimulates ARE-mRNA Decay. PLOS ONE 9:-(2014).
- Adolph, C; Akhunzyanov, R; et al. Measurement of radiative widths of a(2)(1320) and pi(2)(1670). EUROPEAN PHYSICAL JOURNAL A 50:-(2014).
