BIN3
-
Official Full Name
bridging integrator 3 -
Overview
The product of this gene is a member of the BAR domain protein family. The encoded protein is comprised solely of a BAR domain which is predicted to form coiled-coil structures and proposed to mediate dimerization, sense and induce membrane curvature, and bind small GTPases. BAR domain proteins have been implicated in endocytosis, intracellular transport, and a diverse set of other processes. -
Synonyms
BIN3;bridging integrator 3;BIN3_HUMAN;MGC14978;OTTHUMP00000225122;OTTHUMP00000225124;OTTHUMP00000225126
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Rat
- Wheat Germ
- Mammalian Cell
- HEK293
- In Vitro Cell Free System
- HEK293T
- GST
- His
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
BIN3 involved in several pathways and played different roles in them. We selected most pathways BIN3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with BIN3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
BIN3 has several biochemical functions, for example, cytoskeletal adaptor activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BIN3 itself. We selected most functions BIN3 had, and list some proteins which have the same functions with BIN3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | SPEF2,TXNDC12,MAP2K4,RNF149,FAM118A,PSMB2,RHOH,ARHGEF16,RAB39B,TCAP |
| cytoskeletal adaptor activity | SORBS2,NCK1,GAS2L2,BAIAP2L1A,BAIAP2L1B,ABI2,SDCBP,BAIAP2L1,GAS2L1,NCK2 |
Interacting Protein
BIN3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BIN3 here. Most of them are supplied by our site. Hope this information will be useful for your research of BIN3.
DNMBP
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