BEX2
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Official Full Name
brain expressed X-linked 2 -
Overview
This gene belongs to the brain expressed X-linked gene family. The encoded protein interacts with the transcription factor LIM domain only 2 in a DNA-binding complex that recognizes the E-box element and promotes transcription. This gene has been found to be a tumor suppressor that is silenced in human glioma. In breast cancer cells, this gene product modulates apoptosis in response to estrogen and tamoxifen, and enhances the anti-proliferative effect of tamoxifen. Multiple transcript variants encoding different isoforms have been found for this gene. -
Synonyms
BEX2;brain expressed X-linked 2;protein BEX2;DJ79P11.1;BEX 1;BEX 2;BEX1;Brain expressed X linked 2;Brain expressed X linked protein 2 homolog;brain expressed X-linked 1;HBEX2;HGR74-h;uncharacterized hypothalamus protein HBEX2;X-linked protein;OTTHUMP00000023734;OTTHUMP00000023735;OTTHUMP00000023736;brain-expressed X-linked protein 2
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| BEX2-972R | Recombinant Rat BEX2 Protein | Mammalian Cell | Rat | His |
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| BEX2-8463HCL | Recombinant Human BEX2 293 Cell Lysate | HEK293 | Human | Non |
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| BEX2-2596H | Recombinant Human BEX2 Protein, His-tagged | E.coli | Human | His |
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| BEX2-630R | Recombinant Rat BEX2 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| BEX2-630R-B | Recombinant Rat BEX2 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| Bex2-704M | Recombinant Mouse Bex2 Protein, MYC/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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Involved Pathway
BEX2 involved in several pathways and played different roles in them. We selected most pathways BEX2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with BEX2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
BEX2 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BEX2 itself. We selected most functions BEX2 had, and list some proteins which have the same functions with BEX2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | FAM124A,HIST1H1C,Il4ra,TWIST2,INPP4B,ACSF2,SPRED2,LRPAP1,TRAPPC6B,BOC |
Interacting Protein
BEX2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BEX2 here. Most of them are supplied by our site. Hope this information will be useful for your research of BEX2.
TRIM42;FSD2;NECAB2;KRT38;TRIM27;KRT15;KRTAP5-9
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