BCO2
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Official Full Name
beta-carotene oxygenase 2 -
Overview
This gene encodes an enzyme which oxidizes carotenoids such as beta-carotene during the biosynthesis of vitamin A.;Multiple transcript variants encoding different isoforms have been found for this gene. -
Synonyms
BCO2;beta-carotene oxygenase 2;BCDO2, beta carotene dioxygenase 2;beta,beta-carotene 9,10-oxygenase;B DIOX II;beta carotene 9;10 oxygenase;FLJ34464;beta-carotene dioxygenase 2;beta-carotene 9,10 oxygenase;b,b-carotene-9,10-dioxygenase;beta,bet
Recombinant Proteins
- Human
- Cynomolgus
- Mammalian Cell
- Wheat Germ
- In Vitro Cell Free System
- HEK293
- His
- GST
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| BCO2-1073H | Recombinant Human BCO2 | Mammalian Cell | Human | His |
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| BCO2-173H | Recombinant Human BCO2 Protein, GST-tagged | Wheat Germ | Human | GST |
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| BCO2-340C | Recombinant Cynomolgus BCO2 Protein, His-tagged | Mammalian Cell | Cynomolgus | His |
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| BCO2-1556HF | Recombinant Full Length Human BCO2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 539 amino acids |
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| BCO2-2539H | Recombinant Human BCO2 Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
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| BCO2-2539H-B | Recombinant Human BCO2 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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| BCO2-88C | Recombinant Cynomolgus Monkey BCO2 Protein, His (Fc)-Avi-tagged | HEK293 | Cynomolgus | His&Fc&Avi |
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| BCO2-88C-B | Recombinant Cynomolgus Monkey BCO2 Protein Pre-coupled Magnetic Beads | HEK293 | Cynomolgus |
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Involved Pathway
BCO2 involved in several pathways and played different roles in them. We selected most pathways BCO2 participated on our site, such as Retinoid metabolism and transport,Signal Transduction,Visual phototransduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with BCO2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Visual phototransduction | METAP2B,ABCA4A,RDH12,SDR9C7,RGS9BP,RPE65B,APOA4A,MYO7AA,LRP10,RDH10 |
| Retinoid metabolism and transport | AKR1C6,APOM,RBP1,APOC2,RBP2A,LRP12,BCO2L,APOA4B.1,CLPS,BCO2A |
| Vitamin A and carotenoid metabolism | RDH12,RDH10,RBP7,CRABP2,CRABP1,RARG,DHRS3 |
| Signal Transduction | RGS7,ARHGEF18A,QRFP,SH2B3,OXGR1A.2,INHBAA,ADM2,ADM2A,SOX6,RHOU |
Protein Function
BCO2 has several biochemical functions, for example, metal ion binding,oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen. Some of the functions are cooperated with other proteins, some of the functions could acted by BCO2 itself. We selected most functions BCO2 had, and list some proteins which have the same functions with BCO2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metal ion binding | FOLH1,ZDHHC1,RXFP1,ZFP41,ZBTB3,ZDHHC22,NEURL3,RPE,TRIM35,PIR |
| oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen | ALOX5B.3,ALOX12,ALOX8,ALOX12B,P4HA3,ADOB,ALOX5A,P4HA1A,TMLHE,P4HA1B |
Interacting Protein
BCO2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BCO2 here. Most of them are supplied by our site. Hope this information will be useful for your research of BCO2.
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