BBOX1
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Official Full Name
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 -
Overview
This gene encodes gamma butyrobetaine hydroxylase which catalyzes the formation of L-carnitine from gamma-butyrobetaine, the last step in the L-carnitine biosynthetic pathway. Carnitine is essential for the transport of activated fatty acids across the mitochondrial membrane during mitochondrial beta-oxidation. -
Synonyms
BBOX1;butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1;BBOX;gamma-butyrobetaine dioxygenase;BBH;G BBH;gamma BBH;gamma-butyrobetaine hydroxylase;gamma-butyrobetaine,2-oxoglutarate dioxygenase 1;G-BBH;gamma-BBH
Recombinant Proteins
- Human
- Zebrafish
- Rat
- Mouse
- E.coli
- Wheat Germ
- Mammalian Cells
- Insect Cells
- In Vitro Cell Free System
- HEK293
- His
- GST
- Non
- Myc
- DDK
- Avi
- Fc
Involved Pathway
BBOX1 involved in several pathways and played different roles in them. We selected most pathways BBOX1 participated on our site, such as Lysine degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with BBOX1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Lysine degradation | COLGALT2,ALDH1B1,C2orf34,SUV39H1A,SUV39H1,OGDHA,EHMT1B,SETD1BA,ALDH9A1,SETD1B |
Protein Function
BBOX1 has several biochemical functions, for example, gamma-butyrobetaine dioxygenase activity,iron ion binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BBOX1 itself. We selected most functions BBOX1 had, and list some proteins which have the same functions with BBOX1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| iron ion binding | CYP4V8,HBAD,HBG1,EGLN1,CYP4F14,CYP4F12,BRSK2,FTH1,TMLHE,CYP17A1 |
| zinc ion binding | TMEM163,LIMK1,PARP1,LTN1,LMO7A,ABLIM1A,ADAM5,LDB3A,ACE,CA8 |
| protein binding | TTC17,DVL3,GATA2,CDK15,NGF,AHCYL2,ATOX1,IL11,SCAMP5,C19orf44 |
Interacting Protein
BBOX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BBOX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of BBOX1.
SHTN1;HSPB3
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