BACH2
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Official Full Name
BTB and CNC homology 2
Recombinant Proteins
- Human
- Mouse
- E.coli
- Wheat Germ
- HEK293
- Insect Cell
- In Vitro Cell Free System
- HEK293T
- Mammalian cells
- GST
- Non
- His&Strep
- His&Fc&Avi
- Myc&DDK
- His
- Flag
Involved Pathway
BACH2 involved in several pathways and played different roles in them. We selected most pathways BACH2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with BACH2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
BACH2 has several biochemical functions, for example, RNA polymerase II distal enhancer sequence-specific DNA binding,transcription factor activity, sequence-specific DNA binding,transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BACH2 itself. We selected most functions BACH2 had, and list some proteins which have the same functions with BACH2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA polymerase II distal enhancer sequence-specific DNA binding | HOXB5,MED12,SPI1,ATF2,H3F3B,ARX,SOX10,SFPQ,H2AFZ,ESRRB |
| transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding | BACH1,MSC,ZBTB16,PAX4,GZF1,PROP1,ARX |
| transcription factor activity, sequence-specific DNA binding | KAT7,HNF1A,NR1D1,ZNF773,RFX5,ZNF213,SREBF1,PTTG1,RORAA,LMO4 |
| contributes_to ubiquitin-protein transferase activity | KLHL24A,KLHL41,ERCC8,KBTBD13,FBXL15,KBTBD12,KLHDC5,BTRC,KLHL14,KBTBD5 |
Interacting Protein
BACH2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BACH2 here. Most of them are supplied by our site. Hope this information will be useful for your research of BACH2.
sbcC;il2_human_gene;ARRB1
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References
- Watanabe-Matsui, M; Matsumoto, T; et al. Heme binds to an intrinsically disordered region of Bach2 and alters its conformation. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 565:25-31(2015).
- White, CA; Pone, EJ; et al. Histone Deacetylase Inhibitors Upregulate B Cell microRNAs That Silence AID and Blimp-1 Expression for Epigenetic Modulation of Antibody and Autoantibody Responses. JOURNAL OF IMMUNOLOGY 193:5933-5950(2014).
