AUP1
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Official Full Name
ancient ubiquitous protein 1 -
Overview
This gene encodes a protein that contains a domain with homology to the ancient conserved region of the archain 1 gene and a domain that may be involved in binding ubiquitin-conjugating enzymes. The protein encoded by this gene has been shown to bind to the conserved membrane-proximal sequence of the cytoplasmic tail of integrin alpha(IIb) subunits. These subunits play a crucial role in the integrin alpha(IIb)beta(3) inside-out signalling in platelets and megakaryocytes that leads to platelet aggregation and thrombus formation. This gene overlaps the gene for mitochondrial serine protease 25. -
Synonyms
AUP1;ancient ubiquitous protein 1
Recombinant Proteins
- Zebrafish
- Human
- Rat
- Mouse
- Xenopus laevis
- Mus musculus
- Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
- Mammalian Cell
- Wheat Germ
- E.Coli or Yeast
- HEK293
- E.coli
- In Vitro Cell Free System
- E.coli expression system
- His
- GST
- Non
- His&GST
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| AUP1-10088Z | Recombinant Zebrafish AUP1 | Mammalian Cell | Zebrafish | His |
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| AUP1-1036H | Recombinant Human AUP1 protein, GST-tagged | Wheat Germ | Human | GST |
|
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| Aup1-3450R | Recombinant Rat Aup1, His-tagged | E.Coli or Yeast | Rat | His | 410 |
|
| AUP1-903R | Recombinant Rat AUP1 Protein | Mammalian Cell | Rat | His |
|
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| AUP1-54HCL | Recombinant Human AUP1 lysate | HEK293 | Human | Non |
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| AUP1-0705H | Recombinant Human AUP1 Protein (Val201-Asp410), His tagged | E.coli | Human | His | Val201-Asp410 |
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| AUP1-1544HF | Recombinant Full Length Human AUP1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 410 amino acids |
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| AUP1-528H | Recombinant Human AUP1 Protein, His-tagged | E.coli | Human | His | Val201~Asp410 |
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| Aup1529M | Recombinant Mouse Aup1 Protein, His/GST-tagged | E.coli | Mouse | His&GST | Val201~Glu410 |
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| AUP1-559R | Recombinant Rat AUP1 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| AUP1-559R-B | Recombinant Rat AUP1 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| RFL13665RF | Recombinant Full Length Rat Ancient Ubiquitous Protein 1(Aup1) Protein, His-Tagged | E.coli expression system | Rat | His | Full L. Full Length (1-410) |
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| RFL21079XF | Recombinant Full Length Xenopus Laevis Ancient Ubiquitous Protein 1(Aup1) Protein, His-Tagged | E.coli expression system | Xenopus laevis | His | Full L. Full Length (1-399) |
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| RFL35464MF | Recombinant Full Length Mouse Ancient Ubiquitous Protein 1(Aup1) Protein, His-Tagged | E.coli expression system | Mus musculus | His | Full L. Full Length (1-410) |
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| RFL35936XF | Recombinant Full Length Xenopus Tropicalis Ancient Ubiquitous Protein 1(Aup1) Protein, His-Tagged | E.coli expression system | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | His | Full L. Full Length (1-403) |
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Involved Pathway
AUP1 involved in several pathways and played different roles in them. We selected most pathways AUP1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with AUP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
AUP1 has several biochemical functions, for example, protein binding,ubiquitin binding,ubiquitin-protein transferase activator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by AUP1 itself. We selected most functions AUP1 had, and list some proteins which have the same functions with AUP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | NPAS2,CCDC151,ESR2,VLDLR,FBXO28,RAD23B,CD19,PHB,THOP1,SH3GLB1 |
| ubiquitin binding | C6orf106,IWS1,UBAP1,UBE2NB,SHRPRBCK1R,USP16,OTUB1,CRY2,BRAP,TOM1L1 |
| ubiquitin-protein transferase activator activity | UBE2L3,RING1,FBXW7,CBX8 |
Interacting Protein
AUP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AUP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of AUP1.
OPRM1;5901994;ATG12;Oprd1;OPRK1;MAGEA6;UBE2G2;CLN3;ILK;NDN;BRF2;glgA;vanS;UBE2E3;RNF11;1C;P
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