ATRIP
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Official Full Name
ATR interacting protein -
Overview
In response to genomic stress, the ATR interacting protein (ATRIP) binds and is phosphorylated by the DNA damage-and checkpoint-activated kinase ATR (ataxia-telangiectasia mutated and rad3-related). Both ATR and ATRIP are integral for checkpoint signaling -
Synonyms
ATRIP;ATR interacting protein;ATR-interacting protein;FLJ12343;MGC20625;MGC21482;MGC26740;ATM and Rad3-related-interacting protein;DKFZp762J2115
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Chicken
- E.coli
- Wheat Germ
- Mammalian Cell
- HEK293
- Mammalian cells
- HEK293T
- In Vitro Cell Free System
- GST
- His
- Non
- Flag
- Myc&DDK
- His&Fc&Avi
Involved Pathway
ATRIP involved in several pathways and played different roles in them. We selected most pathways ATRIP participated on our site, such as Fanconi anemia pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATRIP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Fanconi Anemia Pathway | C19orf40,FANCD2,POLK,HES1,RAD51,TOP3B,BRIP1,BRCA1,REV3L,RMI2 |
Protein Function
ATRIP has several biochemical functions, for example, K63-linked polyubiquitin binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ATRIP itself. We selected most functions ATRIP had, and list some proteins which have the same functions with ATRIP. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | HELT,RCC2,CMKLR1,NUDT21,PGRMC1,TSPAN2,SMR3B,ZNHIT1,POP1,GATA5 |
| K63-linked polyubiquitin binding | OTUD7B,ZRANB1B,ZRANB1,PRPF8,RNF168,UIMC1,SPRTN,ZRANB3,TNFAIP3,SQSTM1 |
Interacting Protein
ATRIP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATRIP here. Most of them are supplied by our site. Hope this information will be useful for your research of ATRIP.
POLR1C;SPRY2;MOS;SCG2;MX2;CDK9;FAM208B
ATRIP Related Signal Pathway
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References
