ATOH1
-
Official Full Name
atonal homolog 1 -
Overview
This protein belongs to the basic helix-loop-helix (BHLH) family of transcription factors. It activates E-box dependent transcription along with E47. -
Synonyms
ATOH1;atonal homolog 1 (Drosophila);protein atonal homolog 1;bHLHa14;HATH1;MATH 1;Math1;helix-loop-helix protein hATH-1;class A basic helix-loop-helix protein 14;ATH1;MATH-1
Recombinant Proteins
- Human
- Mouse
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- Yeast
- In Vitro Cell Free System
- His
- GST
- Non
- His&SUMO
- His&Fc&Avi
Involved Pathway
ATOH1 involved in several pathways and played different roles in them. We selected most pathways ATOH1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ATOH1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
ATOH1 has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding,chromatin DNA binding,protein dimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ATOH1 itself. We selected most functions ATOH1 had, and list some proteins which have the same functions with ATOH1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA polymerase II core promoter proximal region sequence-specific DNA binding | FOXD1,ZNF257,MED8,MIXL1,OTX1,CTCFL,KCNIP3,SMAD2,MYF6,HOXA7 |
| chromatin DNA binding | PER1,HIST1H1C,HIST1H1B,HDAC3,GRHL2,ZIC2,SMAD3,RXRA,HIST1H1E,BCL6 |
| protein dimerization activity | CLOCK,STRA8,TFEB,HER4.2,NCOA1,NCOA3,HPS1,AHR1A,FBXW11B,TFAP2C |
| transcription factor activity, sequence-specific DNA binding | TARDBP,RXRBA,HMGA1A,E2F5,NR2F6,MYF6,POU3F3,SCAND2P,NFKB1,NFIA |
| transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | MAFB,MEOX2,MIXL1,PITX3,MYB,ZNF750,NFIC,HNF4A,GATA1,MYC |
Interacting Protein
ATOH1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATOH1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ATOH1.
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