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ATAD2

  • Official Full Name

    ATPase family, AAA domain containing 2

  • Overview

    A large family of ATPases has been described, whose key feature is that they share a conserved region of about 220 amino acids that contains an ATP-binding site. The proteins that belong to this family either contain one or two AAA (ATPases Associated with diverse cellular Activities) domains. AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes. The protein encoded by this gene contains two AAA domains, as well as a bromodomain.

  • Synonyms

    ATAD2;ATPase family, AAA domain containing 2;ATPase family AAA domain-containing protein 2;DKFZp667N1320;MGC5254;MGC29843;PRO2000;AAA nuclear coregulator cancer-associated protein;ANCCA;ATAD2_HUMAN;ATPase family AAA domain containing 2;ATPase family AAA domain containing protein 2;MGC131938;MGC142216

Recombinant Proteins

  • Human
  • Wheat germ
  • E.coli
  • HEK293
  • E. coil
  • Wheat Germ
  • In Vitro Cell Free System
  • His&Flag
  • GST
  • Non
  • His
Cat.# Product name Source (Host) Species Tag Protein Length Price
ATAD2-31H Active Recombinant Human ATAD2, His&Flag-tagged E.coli Human His&Flag 981-1108 a.a.
ATAD2-51H Recombinant Human ATAD2 protein, GST-tagged E.coli Human GST 981-1146
ATAD2-8636HCL Recombinant Human ATAD2 293 Cell Lysate HEK293 Human Non
ATAD2-0128H Recombinant Human ATAD2 Protein (Ser245-Glu396), N-His-tagged E.coli Human His Ser245-Glu396
ATAD2-02H Recombinant Human ATAD2 Protein, GST-tagged E. coil Human GST 981-1108 a.a.
ATAD2-10H Recombinant Human ATAD2, GST-tagged Wheat Germ Wheat germ Non
ATAD2-32HF Recombinant Full Length Human ATAD2 Protein, GST-tagged In Vitro Cell Free System Human Full L.

    Involved Pathway

    ATAD2 involved in several pathways and played different roles in them. We selected most pathways ATAD2 participated on our site, such as Gastric cancer network 2, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATAD2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Gastric cancer network 2 BRIX1,CHTF8,CEBPZ,TOP2A,SNRPN,RNF144B,PLAC8,SNURF,DSCC1,CHTF18

    Protein Function

    ATAD2 has several biochemical functions, for example, ATP binding,ATPase activity,chromatin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ATAD2 itself. We selected most functions ATAD2 had, and list some proteins which have the same functions with ATAD2. You can find most of the proteins on our site.

    Function Related Protein
    histone binding HIST1H3D,HIST1H3H,JAK2,NPM1,SART3,HIST1H4K,HIST1H3C,HIST3H3,L3MBTL2,NOC2L
    ATPase activity RNF213,ABCB1A,KIF15,CLPB,ABCB3L1,ABCA5,ATP13A,ABCD1,KIF20A,IDE
    ATP binding PRKAA1,DYRK4,ACTB1,EGFR,SPATA5,TSSK4,ITPKC,PRKACB,PFKM,UBE2NB
    chromatin binding NPM2,CREB3,NFATC2,FOS,SIN3B,CRTC2,NFKB1,NR5A1B,RELB,PDX1

    Interacting Protein

    ATAD2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATAD2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ATAD2.

    SPTBN2;BCAR3;BAG4;ESR1;CASP8;CD247;Naa50;HDAC11

    Resources

    Research Area

    Breast Cancer Biomarkers
    Colon Cancer Biomarkers
    Gastric Cancer Biomarkers
    Liver Cancer Biomarkers
    Lung Cancer Biomarkers
    Ovarian Cancer Biomarkers

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