Asic2
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Official Full Name
acid-sensing (proton-gated) ion channel 2
Recombinant Proteins
- Zebrafish
- Rhesus macaque
- Rat
- Human
- Mouse
- Mammalian Cell
- HEK293
- HEK293T
- His
- Non
- His&Fc&Avi
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ASIC2-12803Z | Recombinant Zebrafish ASIC2 | Mammalian Cell | Zebrafish | His |
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| ASIC2-427R | Recombinant Rhesus monkey ASIC2 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| ASIC2-822R | Recombinant Rat ASIC2 Protein | Mammalian Cell | Rat | His |
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| ASIC2-9103HCL | Recombinant Human ACCN1 293 Cell Lysate | HEK293 | Human | Non |
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| ASIC2-256R | Recombinant Rhesus Macaque ASIC2 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| ASIC2-256R-B | Recombinant Rhesus Macaque ASIC2 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| ASIC2-478R | Recombinant Rat ASIC2 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| ASIC2-478R-B | Recombinant Rat ASIC2 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| Asic2-508M | Recombinant Mouse Asic2 Protein, MYC/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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Involved Pathway
Asic2 involved in several pathways and played different roles in them. We selected most pathways Asic2 participated on our site, such as Taste transduction,Inflammatory mediator regulation of TRP channels, which may be useful for your reference. Also, other proteins which involved in the same pathway with Asic2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Taste transduction | TAS2R3,TAS2R123,TAS2R13,TAS2R120,TAS2R118,TRPM5,PRKACB,TAS2R20,TAS2R40,ITPR3 |
| Inflammatory mediator regulation of TRP channels | ACCN5,PIK3CG,ACCN4,PTGER4,ITPR3,NGF,ASIC4,PRKCD,KLK1B4,MAPK13 |
Protein Function
Asic2 has several biochemical functions, for example, ligand-gated sodium channel activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Asic2 itself. We selected most functions Asic2 had, and list some proteins which have the same functions with Asic2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | RHO,LTC4S,RTF1,ANXA10,LCORL,PSMD5,DDX39B,NR3C1,KIF9,BACH1 |
| ligand-gated sodium channel activity | ASIC1B,ACCN3,ASIC1A,ASIC1,ASIC3,ASIC1C,ASIC4A,SCNN1D,ACCN5,ASIC5 |
Interacting Protein
Asic2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Asic2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Asic2.
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References
- Cabo, R; Alonso, P; et al. ASIC2 is present in human mechanosensory neurons of the dorsal root ganglia and in mechanoreceptors of the glabrous skin. HISTOCHEMISTRY AND CELL BIOLOGY 143:267-276(2015).
- Gannon, KP; Mckey, SE; et al. Altered myogenic vasoconstriction and regulation of whole kidney blood flow in the ASIC2 knockout mouse. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY 308:F339-F348(2015).
