ASCL1A
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Official Full Name
achaete-scute complex-like 1a (Drosophila) -
Synonyms
ASCL1A;achaete-scute complex-like 1a (Drosophila);achaete-scute homolog 1a;Achaete scute homolog 1a;ash;ash1a;asha;pia;Pituitary absent protein;Zash 1a;pituitary absent;pituitary-absent protein;zasha;zash1a;Zash-1a;id:ibd5085;im:7138587;si:dkey-264k15.2
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ASCL1A-8820Z | Recombinant Zebrafish ASCL1A | Mammalian Cell | Zebrafish | His |
|
Involved Pathway
ASCL1A involved in several pathways and played different roles in them. We selected most pathways ASCL1A participated on our site, such as Delta-Notch Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ASCL1A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Delta-Notch Signaling Pathway | JAG2,RING1,SMAD3B,HEY2,CNTFR,CNTF,MAGEA1,JAG1,YY1A,APPA |
Protein Function
ASCL1A has several biochemical functions, for example, DNA binding,protein dimerization activity,sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ASCL1A itself. We selected most functions ASCL1A had, and list some proteins which have the same functions with ASCL1A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcription factor activity, transcription factor binding | LDB2B,LDB1B,LDB2A,PER1,CRY2,CRY1,FOXO1,NEUROG1,MTA2,LDB1A |
| DNA binding | SLC2A4RG,ZBTB8A,POLR2F,IMPDH2,DLX3B,SUPV3L1,NR0B2,ZNF280A,UBN1,IRF1 |
| protein dimerization activity | NEUROD6,MNTB,MESPBB,LYL1,NLGN1,MEF2CB,TFAP2C,ATOH1,GARS,HER2 |
| sequence-specific DNA binding | HOXC13B,FOXM1,BATF,FOXI1,HOXA9B,LBX1A,ZSCAN4,CSRNP1,CHES1,ZIC3 |
Interacting Protein
ASCL1A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ASCL1A here. Most of them are supplied by our site. Hope this information will be useful for your research of ASCL1A.
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References
- Solin, SL; Wang, Y; et al. Molecular and Cellular Characterization of a Zebrafish Optic Pathway Tumor Line Implicates Glia-Derived Progenitors in Tumorigenesis. PLOS ONE 9:-(2014).
- Conner, C; Ackerman, KM; et al. Repressing Notch Signaling and Expressing TNF alpha Are Sufficient to Mimic Retinal Regeneration by Inducing Muller Glial Proliferation to Generate Committed Progenitor Cells. JOURNAL OF NEUROSCIENCE 34:14403-14419(2014).
