ASB9
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Official Full Name
ankyrin repeat and SOCS box containing 9 -
Overview
This gene encodes a member of the ankyrin repeat and suppressor of cytokine signaling (SOCS) box protein family. Members of this family can interact with the elongin B-C adapter complex via their SOCS box domain and further complex with the cullin and ring box proteins to form E3 ubiquitin ligase complexes. They may function to mediate the substrate-recognition of the E3 ubiquitin ligases. A transcribed pseudogene of this gene has been identified on chromosome 15. Multiple transcript variants encoding different isoforms have been found for this gene. -
Synonyms
ASB9;ankyrin repeat and SOCS box containing 9;ankyrin repeat and SOCS box protein 9;DKFZP564L0862;FLJ20636;MGC4954;ASB-9;ankyrin repeat and SOCS box-containing 9;ankyrin repeat and suppressor of cytokine signaling box protein 9
Recombinant Proteins
- Human
- Chicken
- Mouse
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- HEK293T
- GST
- His
- Non
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ASB9-9921H | Recombinant Human ASB9, GST-tagged | E.coli | Human | GST | 1-252a.a. | |
| ASB9-1409C | Recombinant Chicken ASB9 | Mammalian Cell | Chicken | His |
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| ASB9-2021M | Recombinant Mouse ASB9 Protein | Mammalian Cell | Mouse | His |
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| ASB9-898H | Recombinant Human ASB9 protein, GST-tagged | Wheat Germ | Human | GST |
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| ASB9-8657HCL | Recombinant Human ASB9 293 Cell Lysate | HEK293 | Human | Non |
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| ASB9-8658HCL | Recombinant Human ASB9 293 Cell Lysate | HEK293 | Human | Non |
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| ASB9-1364HF | Recombinant Full Length Human ASB9 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 252 amino acids |
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| Asb9-1736M | Recombinant Mouse Asb9 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| ASB9-5738H | Recombinant Human ASB9 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| ASB9-781M | Recombinant Mouse ASB9 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| ASB9-781M-B | Recombinant Mouse ASB9 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
ASB9 involved in several pathways and played different roles in them. We selected most pathways ASB9 participated on our site, such as Adaptive Immune System,Antigen processing: Ubiquitination &,Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with ASB9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Class I MHC mediated antigen processing & | FBXO27,RNF111,RNF182,HECTD3,KLHL20,UBE2L6,WWP1,STUB1,DTX3L,FBXO3 |
| Immune System | PIK3AP1,KIF11,NCR3LG1,ALCAMB,BTLA,ABI1B,DEFA3,TNIP2,FCN2,MKRN1 |
| Antigen processing: Ubiquitination & | FBXO27,RNF25,TRIM9,RNF138,ASB3,RBCK1,HECTD3,ASB18,RNF4,FBXO17 |
| Proteasome degradation | UBE2U,RBCK1,ASB17,LRSAM1,SPSB1,TPP2,ASB2,UBE2F,ARIH2,ASB11 |
| Adaptive Immune System | UBE2V1,TREML2,CTLA4,FBXO17,LILRB3,ARIH2,MICA,Siglece,PVRL2L,DYNC1I2 |
| presentation | VPRBP,RNF19B,TRIM41,ATG7,LRRC41,RNF182,UBE2L6,KLHL21,SPSB4,CTSL1 |
Protein Function
ASB9 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ASB9 itself. We selected most functions ASB9 had, and list some proteins which have the same functions with ASB9. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | TTC1,CD1d1,SMAD3B,FAM114A1,DNER,MTF1,LETMD1,DCX,ZFAND6,FSHB |
Interacting Protein
ASB9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ASB9 here. Most of them are supplied by our site. Hope this information will be useful for your research of ASB9.
CKB;CKM;HIF1AN;HEL-S-29;CRK;PLCG2;Tceb1
Resources
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References
- Fingert, JH; Roos, BR; et al. Analysis of ASB10 variants in open angle glaucoma. HUMAN MOLECULAR GENETICS 21:4543-4548(2012).
- Zhang, LF; Zhou, X; et al. Genome Wide Screening of Candidate Genes for Improving Piglet Birth Weight Using High and Low Estimated Breeding Value Populations. INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES 10:236-244(2014).
