ASB4

  • Official Full Name

    ankyrin repeat and SOCS box containing 4

  • Overview

    The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants have been described for this gene but some of the full length sequences are not known.

  • Synonyms

    ASB4;ankyrin repeat and SOCS box containing 4;ankyrin repeat and SOCS box protein 4;ASB 4;Ankyrin repeat and SOCS box containing protein 4;ankyrin repeat and SOCS box-containing 4;ASB-4

Recombinant Proteins

  • Mouse
  • Zebrafish
  • Human
  • Mammalian Cell
  • Wheat Germ
  • HEK293
  • In Vitro Cell Free System
  • His
  • GST
  • Non
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
ASB4-2016M Recombinant Mouse ASB4 Protein Mammalian Cell Mouse His
ASB4-2399Z Recombinant Zebrafish ASB4 Mammalian Cell Zebrafish His
ASB4-893H Recombinant Human ASB4 protein, GST-tagged Wheat Germ Human GST
ASB4-8662HCL Recombinant Human ASB4 293 Cell Lysate HEK293 Human Non
ASB4-8663HCL Recombinant Human ASB4 293 Cell Lysate HEK293 Human Non
ASB4-1296HF Recombinant Full Length Human ASB4 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 319 amino acids
ASB4-779M Recombinant Mouse ASB4 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
ASB4-779M-B Recombinant Mouse ASB4 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    ASB4 involved in several pathways and played different roles in them. We selected most pathways ASB4 participated on our site, such as Adaptive Immune System,Antigen processing: Ubiquitination &amp,Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with ASB4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    presentation DZIP3,UBE2F,MKRN1,RNF4,LRR1,CYBA,CD207,ASB3,ARIH2,UBR1
    Adaptive Immune System LAIR2,UBR1,CREB1,CTSS,Mill2,KIF20A,KLRF1,CD200R1,UBE2E3,ASB17
    Immune System CD160,CFHL2,UBE2E3,DEFB106A,SIRPB1,ASB2,TXN,CLEC2H,ASB3,CD300LD
    Proteasome degradation KLHL20,RNF34,RNF6,TRIM39,PJA2,UBA5,PJA1,TRIM63,TPP2,ASB10
    Antigen processing: Ubiquitination &amp RNF14,UFL1,ASB6,RNF111,UBE2L6,DTX3L,RNF19B,KLHL21,DZIP3,ASB18
    Class I MHC mediated antigen processing &amp FBXO3,ASB8,RNF19B,ATG7,KLHL21,TRIM11,MKRN1,GAN,CD207,FCGR1B

    Protein Function

    ASB4 has several biochemical functions, for example, ubiquitin protein ligase activity,ubiquitin protein ligase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ASB4 itself. We selected most functions ASB4 had, and list some proteins which have the same functions with ASB4. You can find most of the proteins on our site.

    Function Related Protein
    ubiquitin protein ligase binding CCDC50,MDM2,PER3,ERBB2,MOAP1,GLMN,UBE2KB,EGFR,GPI1,UBE2V1
    ubiquitin protein ligase activity ARIH1,MED10,FBXL22,RNF24,UBE2B,RNF144AB,RNF222,UBE3B,UBE2S,BTRC

    Interacting Protein

    ASB4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ASB4 here. Most of them are supplied by our site. Hope this information will be useful for your research of ASB4.

    HSP90AB1

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