ASB3
-
Official Full Name
ankyrin repeat and SOCS box containing 3 -
Overview
The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Alternatively spliced transcript variants have been described for this gene. -
Synonyms
ASB3;ankyrin repeat and SOCS box containing 3;ankyrin repeat and SOCS box protein 3;ASB 3;Ankyrin repeat and SOCS box containing protein 3;ASB-3;ASB3_HUMAN;FLJ10123;FLJ10421;MGC12531;MGC132002;MGC996;Weakly similar to ankyrin brain variant 2
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- Chicken
- Cynomolgus
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- HEK293T
- His
- T7
- GST
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
ASB3 involved in several pathways and played different roles in them. We selected most pathways ASB3 participated on our site, such as Adaptive Immune System,Antigen processing: Ubiquitination &,Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with ASB3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Proteasome degradation | ARIH2,RNF138,DZIP3,CMTM2A,KLHL20,LRRC41,VPRBP,RNF123,UBR1,UBE2F |
| presentation | RNF138,FCGR1B,RNF34,RNF182,RNF6,NPEPPS,B2ML,RNF4,TRIM39,SEC61B |
| Adaptive Immune System | CTSL2,STIM1B,FGFR1B,CLEC2G,NPEPPS,TREML4,UFL1,KIF3B,DYNC1I2,TRIM11 |
| Immune System | UBA5,PVRL2L,GM11711,BTR29,KIF20A,ATG7,KIF3B,RNF216,NLRC5,TAX1BP1 |
| Antigen processing: Ubiquitination & | DTX3L,TRIM50,PJA2,FBXO27,TRIM9,RNF144B,ASB17,RNF182,SPSB1,ASB8 |
| Class I MHC mediated antigen processing & | FBXO17,RNF34,UBE2L6,PJA1,ATG7,UBE2J2,RNF25,TPP2,ASB11,UBE2V1 |
Protein Function
ASB3 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ASB3 itself. We selected most functions ASB3 had, and list some proteins which have the same functions with ASB3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | RECK,TOP2A,CD8B1,CIAO1,CIB4,TAF9B,GTSE1,KATNA1,TPD52L1,UCP3 |
Interacting Protein
ASB3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ASB3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ASB3.
SH2D2A;HSP90AB1;KDM1A;ZAP70;TNS2;RIN3;eno;PRMT6
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