ASAP2

  • Official Full Name

    ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
  • Overview

    PAG3 (paxillin-associated protein with ADP-ribosylation factor [ARF] GTPase-activating protein [GAP] activity, number 3) is a member of the ARF GAP family of proteins that associates with the cytoskeleton, plays an important role in mediating actin cytosk
  • Synonyms

    ASAP2;ArfGAP with SH3 domain, ankyrin repeat and PH domain 2;DDEF2, development and differentiation enhancing factor 2;arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2;centaurin;beta 3;CENTB3;KIAA0400;PAP;SHAG1;centaurin,
Cat.# Product name Source (Host) Species Tag Protein Length Price
ASAP2-9911H Recombinant Human ASAP2, His-tagged E.coli Human His 1-357a.a.
ASAP2-2436H Recombinant Human ASAP2 Protein, GST-tagged Wheat Germ Human GST
ASAP2-3618H Recombinant Human ASAP2, His-tagged E.Coli or Yeast Human His 961
ASAP2-8667HCL Recombinant Human ASAP2 293 Cell Lysate HEK293 Human Non
ASAP2-2445HF Recombinant Full Length Human ASAP2 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 1006 amino acids

    Involved Pathway

    ASAP2 involved in several pathways and played different roles in them. We selected most pathways ASAP2 participated on our site, such as Endocytosis,Fc gamma R-mediated phagocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with ASAP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Endocytosis ADRB2B,ARPC2,TGFB1A,AGAP1,KITB,SH3GLB2A,GRK1A,ARFGAP1,ARRB2A,DNM2B
    Fc gamma R-mediated phagocytosis PPAP2B,FCGR3A,PIK3CA,AKT1,CFL1,PTPRC,MARCKSL1,MARCKS,VAV1,MAP2K1

    Protein Function

    ASAP2 has several biochemical functions, for example, GTPase activator activity,enzyme activator activity,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ASAP2 itself. We selected most functions ASAP2 had, and list some proteins which have the same functions with ASAP2. You can find most of the proteins on our site.

    Function Related Protein
    metal ion binding SDHD,APLF,RUFY4,ZFP110,ALKBH4,KLF7B,PHF23B,ZKSCAN14,RCV1,CYP1D1
    protein binding NIPAL1,SMAD3B,BHLHE40,ARRB2,TRAIP,TLR2,SWAP70,AGBL1,NUTF2,AIP
    GTPase activator activity GNAQ,DEPDC1B,ELMOD2,RIC8A,AGFG1B,OCRL,RIN3,CHN2,RGS14A,ARHGAP31
    enzyme activator activity ALOX5AP,MMP17,RICTOR,OGT,HSPB2,GMFG,MMP16,CLPS,DBF4,RAB3GAP2

    Interacting Protein

    ASAP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ASAP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ASAP2.

    GRB2;apc;PLCG1;q5jpt6_human;UBC;VILL;FYN;SRC;NCK1;PIK3R1

    Resources

    References

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