ARPP21
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Official Full Name
cAMP-regulated phosphoprotein, 21kDa -
Overview
The 21-kD cAMP-regulated phosphoprotein (ARPP21), also known as regulator of calmodulin (CaM; MIM 114180) signaling (RCS), plays a central role in integration of key neurotransmitter inputs into medium spiny neurons through its regulation of CaM-dependent kinase I (CaMKI) and protein phosphatase-2B (PP2B) (Rakhilin et al., 2004 -
Synonyms
ARPP21;cAMP-regulated phosphoprotein, 21kDa;cAMP-regulated phosphoprotein 21;ARPP 21;R3H domain containing 3;R3HDM3;TARPP;thymocyte cAMP-regulated phosphoprotein;cyclic AMP-regulated phosphoprotein, 21 kD;RCS;ARPP-21;FLJ32997
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ARPP21-9890H | Recombinant Human ARPP21, GST-tagged | E.coli | Human | GST | 1-89a.a. | |
| ARPP21-8680HCL | Recombinant Human ARPP21 293 Cell Lysate | HEK293 | Human | Non |
|
Involved Pathway
ARPP21 involved in several pathways and played different roles in them. We selected most pathways ARPP21 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ARPP21 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
ARPP21 has several biochemical functions, for example, calmodulin binding,molecular_function,nucleic acid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ARPP21 itself. We selected most functions ARPP21 had, and list some proteins which have the same functions with ARPP21. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| molecular_function | MFSD12,ARPP19B,CHTOPB,FLOT2A,CX52.7,POMZP3,EMC8,ARHGAP40,TMEM167,ISOC1 |
| nucleic acid binding | NABP2,USP6,U2AF2A,JAZF1B,ZFP524,SCRT1A,RBM4.3,ZFP553,FAM90A1,ZBTB2A |
| calmodulin binding | MYO6,OBSCN,PDE1B,DAPK1,TRPM4,RASGRF2B,PPP3CB,MYO1G,CDK5RAP2,MYO5B |
Interacting Protein
ARPP21 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARPP21 here. Most of them are supplied by our site. Hope this information will be useful for your research of ARPP21.
TERF1;TERF2IP
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References
- Marangi, G; Orteschi, D; et al. Interstitial Deletion of 3p22.3p22.2 Encompassing ARPP21 and CLASP2 is a Potential Pathogenic Factor for a Syndromic Form of Intellectual Disability: A Co-Morbidity Model With Additional Copy Number Variations in a Large Family. AMERICAN JOURNAL OF MEDICAL GENETICS PART A 161:2890-2893(2013).
- Song, JS; Hwang, DH; et al. Comparative Gene Expression Analysis of the Human Periodontal Ligament in Deciduous and Permanent Teeth. PLOS ONE 8:-(2013).
