ARHGAP9
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Official Full Name
Rho GTPase activating protein 9 -
Overview
This gene encodes a member of the Rho-GAP family of GTPase activating proteins. The protein has substantial GAP activity towards several Rho-family GTPases in vitro, converting them to an inactive GDP-bound state. It is implicated in regulating adhesion of hematopoietic cells to the extracellular matrix. Multiple transcript variants encoding different isoforms have been found for this gene. -
Synonyms
ARHGAP9;Rho GTPase activating protein 9;rho GTPase-activating protein 9;10C;MGC1295;RGL1;FLJ16525;Rho type GTPase activating protein 9;rho-type GTPase-activating protein 9
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ARHGAP9-773H | Recombinant Human ARHGAP9 protein, GST-tagged | Wheat Germ | Human | GST |
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| ARHGAP9-114HCL | Recombinant Human ARHGAP9 cell lysate | Human | Non |
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| ARHGAP9-1269HF | Recombinant Full Length Human ARHGAP9 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 750 amino acids |
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| ARHGAP9-1517H | Recombinant Human ARHGAP9 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| ARHGAP9-2701H | Recombinant Human ARHGAP9 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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Involved Pathway
ARHGAP9 involved in several pathways and played different roles in them. We selected most pathways ARHGAP9 participated on our site, such as Regulation of RAC1 activity,Regulation of RhoA activity,Rho GTPase cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with ARHGAP9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Regulation of RAC1 activity | CHN2,RAP1GDS1,ARHGEF25,ARHGAP1,ABR,ARHGAP17,DEF6,CHN1,PREX2,DOCK6 |
| Signaling by Rho GTPases | STARD8,TAGAPB,TAGAP1,ARHGAP25,RHPN2,ABI1A,PLEKHG2,ARHGAP4A,ARHGAP22,RHOT1B |
| Signal Transduction | SPOPL,NPSR1,NOG1,AMOTL2B,ARHGAP29,NPS,LINGO1,RGS9BP,ARHGAP1,FAM123B |
| Regulation of RhoA activity | ECT2,ARHGEF10,DLC1,ARAP1,AKAP13,MCF2L,ARHGAP4,DEF6,OBSCN,MYO9B |
| Rho GTPase cycle | RHOUA,RHOT1,ARHGEF17,GDI1,ARHGAP11A,TAGAPA,GMIP,CHN2,ARHGAP18,AKAP13 |
Protein Function
ARHGAP9 has several biochemical functions, for example, GTPase activator activity,phosphatidylinositol-3,4,5-trisphosphate binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ARHGAP9 itself. We selected most functions ARHGAP9 had, and list some proteins which have the same functions with ARHGAP9. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GTPase activator activity | TBC1D10A,CDC42EP3,ARHGAP28,ARHGAP5,ARHGAP26,ADAP1,NCKAP1L,SMAP2,ALDH1A1,ARHGAP40 |
| phosphatidylinositol-3,4,5-trisphosphate binding | MAPKAP1,GBF1,DAPP1,COMMD1,FERMT2,OGT,RAG2,RACGAP1,ZFYVE1,CYTH3 |
| protein binding | NR1H2,CD200,CHUK,MTCH1,TOMM70A,ISG20L2,GAD2,GDF7,PDLIM5,UBD |
Interacting Protein
ARHGAP9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARHGAP9 here. Most of them are supplied by our site. Hope this information will be useful for your research of ARHGAP9.
GRB2;FHL2;MAPK1;FASLG;MAPK14;SMAD9;q81mm5_bacan;ctc;RBPMS;npm_alk;Mapk1
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