ARHGAP32
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Official Full Name
Rho GTPase activating protein 32 -
Overview
RICS is a neuron-associated GTPase-activating protein that may regulate dendritic spine morphology and strength by;modulating Rho GTPase (see RHOA; MIM 165390) activity (Okabe et al., 2003 (PubMed 12531901)). -
Synonyms
ARHGAP32;Rho GTPase activating protein 32;rho GTPase-activating protein 32;GC GAP;GRIT;KIAA0712;MGC1892;RICS;GAB-associated CDC42;rac GTPase activating protein;rho-type GTPase-activating protein 32;GTPase regulator interacting with TrkA;brain-
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ARHGAP32-1871M | Recombinant Mouse ARHGAP32 Protein | Mammalian Cell | Mouse | His |
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| ARHGAP32-680M | Recombinant Mouse ARHGAP32 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| ARHGAP32-680M-B | Recombinant Mouse ARHGAP32 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
ARHGAP32 involved in several pathways and played different roles in them. We selected most pathways ARHGAP32 participated on our site, such as Rho GTPase cycle,Signal Transduction,Signaling by Rho GTPases, which may be useful for your reference. Also, other proteins which involved in the same pathway with ARHGAP32 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| XPodNet - protein-protein interactions in the podocyte expanded by STRING | SNTB1,CLNK,GAB3,FRAS1,GMCL1,WLS,Siglece,CDC42EP5,TENC1,SDK1 |
| Signal Transduction | QRFPR,STRAP,RLBP1,PDK2,SOX4B,LPAR5A,GPR39,RSPO1,ARHGAP4A,MKL1 |
| Signaling by Rho GTPases | IQGAP3,WIPF3,ARHGAP17,RHPN1,DEPDC7,DEPDC1B,FAM13B1,RHOF,GMIP,ARHGAP26 |
| Rho GTPase cycle | FGD4,RHOT1,ARHGAP4,MYO9B,GDI2,ARHGAP25,ARHGAP33,STARD13,ARHGAP40,ARHGAP17B |
Protein Function
ARHGAP32 has several biochemical functions, for example, GTPase activator activity,phosphatidylinositol binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ARHGAP32 itself. We selected most functions ARHGAP32 had, and list some proteins which have the same functions with ARHGAP32. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GTPase activator activity | AGFG1,TBC1D9B,TBC1D5,GRTP1A,ARHGAP36,RGS5,ARHGAP27,RGS11,ARHGAP42,ADAP1 |
| phosphatidylinositol binding | HIP1,WDR35,PLD1A,ZCCHC2,HIP1RB,ITPR1,CCDC88A,PIK3C2B,NOXO1A,SNX10B |
Interacting Protein
ARHGAP32 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARHGAP32 here. Most of them are supplied by our site. Hope this information will be useful for your research of ARHGAP32.
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