ARHGAP27

  • Official Full Name

    Rho GTPase activating protein 27

  • Overview

    Rho (see ARHA; MIM 165390)-like small GTPases are involved in many cellular processes, and they are inactive in the;GDP-bound state and active in the GTP-bound state. GTPase-activating proteins, such as ARHGAP27, inhibit Rho-like;proteins by stimulating their intrinsic GTPase activity (Katoh and Katoh, 2004 (PubMed 15492870)).

  • Synonyms

    ARHGAP27;Rho GTPase activating protein 27;SH3 domain containing 20 , SH3D20;rho GTPase-activating protein 27;CAMGAP1;FLJ43547;SH3P20;SH3 domain containing 20;SH3 domain-containing protein 20;rho-type GTPase-activating protein 27;CIN85-associated

Recombinant Proteins

  • Mouse
  • Rat
  • Human
  • Mammalian Cell
  • HEK293
  • HEK293T
  • His
  • Non
  • Myc&DDK
  • His&Fc&Avi

    Involved Pathway

    ARHGAP27 involved in several pathways and played different roles in them. We selected most pathways ARHGAP27 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ARHGAP27 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    ARHGAP27 has several biochemical functions, for example, GTPase activator activity,SH3 domain binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ARHGAP27 itself. We selected most functions ARHGAP27 had, and list some proteins which have the same functions with ARHGAP27. You can find most of the proteins on our site.

    Function Related Protein
    SH3 domain binding SH3BGRL2,DTX1,REPS1,KHDRBS2,LYN,KHDRBS1,CIT,CBL,ELMO1,MAPT
    GTPase activator activity ARHGAP19,ARHGDIB,ASAP2A,RGS13,ECT2,TBC1D13,DOCK4,MURC,AGFG1B,RAP1GAP2A

    Interacting Protein

    ARHGAP27 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARHGAP27 here. Most of them are supplied by our site. Hope this information will be useful for your research of ARHGAP27.

    dmsB

    Resources

    References

    • Connelly, TM; Berg, AS; et al. T-cell activation Rho GTPase-activating protein expression varies with inflammation location and severity in Crohn's disease. JOURNAL OF SURGICAL RESEARCH 190:457-464(2014).
    • Au, SLK; Wong, CCL; et al. EZH2-Mediated H3K27me3 Is Involved in Epigenetic Repression of Deleted in Liver Cancer 1 in Human Cancers. PLOS ONE 8:-(2013).

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