ARHGAP12
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Official Full Name
Rho GTPase activating protein 12 -
Overview
This gene encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP);metabolizing enzymes. The encoded protein may be involved in suppressing tumor formation by regulating cell invasion;and adhesion. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. -
Synonyms
ARHGAP12;Rho GTPase activating protein 12;rho GTPase-activating protein 12;FLJ10971;FLJ20737;FLJ21785;Rho type GTPase activating protein 12;rho-type GTPase-activating protein 12
Recombinant Proteins
- Mouse
- Rhesus macaque
- Human
- Mammalian Cell
- Wheat Germ
- In Vitro Cell Free System
- HEK293
- His
- GST
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ARHGAP12-1854M | Recombinant Mouse ARHGAP12 Protein | Mammalian Cell | Mouse | His |
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| ARHGAP12-388R | Recombinant Rhesus monkey ARHGAP12 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| ARHGAP12-761H | Recombinant Human ARHGAP12 protein, GST-tagged | Wheat Germ | Human | GST |
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| ARHGAP12-108HCL | Recombinant Human ARHGAP12 cell lysate | Human | Non |
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| ARHGAP12-1509HF | Recombinant Full Length Human ARHGAP12 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 841 amino acids |
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| ARHGAP12-217R | Recombinant Rhesus Macaque ARHGAP12 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| ARHGAP12-217R-B | Recombinant Rhesus Macaque ARHGAP12 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| ARHGAP12-670M | Recombinant Mouse ARHGAP12 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| ARHGAP12-670M-B | Recombinant Mouse ARHGAP12 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
ARHGAP12 involved in several pathways and played different roles in them. We selected most pathways ARHGAP12 participated on our site, such as Rho GTPase cycle,Signal Transduction,Signaling by Rho GTPases, which may be useful for your reference. Also, other proteins which involved in the same pathway with ARHGAP12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Rho GTPase cycle | ARHGAP25,ARHGAP22,ARHGAP36,NET1,ARHGEF16,FAM13A,PLEKHG2,DLC1,ARHGAP11A,OPHN1 |
| Signal Transduction | ABHD6B,GPRC6A,SOUL4,ARHGAP26,DEPDC1B,ARHGAP29B,NOTUM,CCRL2,MKS1,GREM2 |
| Signaling by Rho GTPases | ARHGAP10,ARHGAP29,ARHGAP36,KIF14,KTN1,DCLRE1B,RHOT1,ARHGAP15,NOXO1A,ARHGEF18A |
Protein Function
ARHGAP12 has several biochemical functions, for example, GTPase activator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ARHGAP12 itself. We selected most functions ARHGAP12 had, and list some proteins which have the same functions with ARHGAP12. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GTPase activator activity | TBC1D17,RASA1,ARHGAP11A,DEPDC1A,GRTP1,RGS3,IQGAP3,CHN2,RAP1GAP2A,FAM13B1 |
Interacting Protein
ARHGAP12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARHGAP12 here. Most of them are supplied by our site. Hope this information will be useful for your research of ARHGAP12.
SRPK2;SRPK1;MAPK11
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