ARCN1

  • Official Full Name

    archain 1

  • Overview

    This gene maps in a region, which include the mixed lineage leukemia and Friend leukemia virus integration 1 genes, where multiple disease-associated chromosome translocations occur. It is an intracellular protein. Archain sequences are well conserved among eukaryotes and this protein may play a fundamental role in eukaryotic cell biology. It has similarities to heat shock proteins and clathrin-associated proteins, and may be involved in vesicle structure or trafficking.

  • Synonyms

    ARCN1;archain 1;coatomer protein complex, subunit delta , COPD;coatomer subunit delta;Archain;Delta coat protein;Delta COP;delta-COP;delta-coat protein;coatomer delta subunit;coatomer protein delta-COP;archain vesicle transport protein 1;coatomer protein complex, subunit delta;COPD

Recombinant Proteins

  • Mouse
  • Chicken
  • Rhesus macaque
  • Human
  • Rat
  • Mammalian Cell
  • Wheat Germ
  • HEK293
  • In Vitro Cell Free System
  • HEK293T
  • His
  • GST
  • Non
  • Myc&DDK
  • His&Fc&Avi

    Involved Pathway

    ARCN1 involved in several pathways and played different roles in them. We selected most pathways ARCN1 participated on our site, such as COPI Mediated Transport,Golgi to ER Retrograde Transport,Membrane Trafficking, which may be useful for your reference. Also, other proteins which involved in the same pathway with ARCN1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    COPI Mediated Transport COPE,COPG,ARF1,TERFA,ARCN1A,ARCN1B,COPB2,COPB1,COPZ1
    Membrane Trafficking COPZ1,AP4B1,NAPB,TBC1D8B,BLOC1S1,EXOC5,TRAPPC5,AP3S1,COPE,ARCN1A
    Golgi to ER Retrograde Transport TERFA,COPB1,ARCN1B,COPG,COPZ1,ARCN1A,COPB2,COPE
    Vesicle-mediated transport TPD52L1,MYO1C,ANKRD28,TGOLN2,TBC1D8B,NECAP1,MIA3,TRAPPC10,TERFA,GJA4

    Protein Function

    ARCN1 has several biochemical functions, for example, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ARCN1 itself. We selected most functions ARCN1 had, and list some proteins which have the same functions with ARCN1. You can find most of the proteins on our site.

    Function Related Protein
    poly(A) RNA binding CROP,HELZ,HIST1H4L,FAM50A,ETF1A,ATP5C1,SMC1A,TIAL1,SNRPD1,RPL5

    Interacting Protein

    ARCN1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARCN1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ARCN1.

    Copa;MYC;KEAP1;TSC22D1;PAN2;PHLDA3;pi3p;1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate;PTBP3;VCAM1;TMED10;Ncstn;e3gl_ade02;Tubg1;SNW1

    Resources

    References

    • Wang, Y; Dong, Z; et al. Identification of differentially expressed proteins in SH-SY5Y cells treated with resveratrol. NEURAL REGENERATION RESEARCH 6:1612-1617(2011).
    • Xu, XJ; Kedlaya, R; et al. Mutation in Archain 1, a Subunit of COPI Coatomer Complex, Causes Diluted Coat Color and Purkinje Cell Degeneration. PLOS GENETICS 6:-(2010).

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