APG8A
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Official Full Name
autophagy-related protein 8a -
Overview
Encodes APG8, a component of autophagy conjugation pathway. Delivered to the lumens of vacuole under nitrogen-starvation condition. Highest expression in flowers. mRNA abundance increased during dark-induced carbon starvation. Predominantly cytoplasmic with or without N starvation. Upon concanamycin A the protein accumulates in the central vacuole as punctuate structures that resemble autophagic bodies. This localization is more abundant upon N starvation. -
Synonyms
APG8A;autophagy-related protein 8a;APG8A (autophagy 8A);AT4G21980;ATG8;ATG8A;Autophagy 8A;Autophagy related protein 8a;Autophagy related ubiquitin like modifier ATG8a;F1N20.80;F1N20_80;AUTOPHAGY 8A (APG8A);FUNCTIONS IN: APG8-specific protease activity, APG8 activating enzyme activity, Atg8 ligase activity;INVOLVED IN: autophagy;LOCATED IN: vacuolar lumen, autophagic vacuole, cytoplasm;EXPRESSED IN: 24 plant structures;EXPRESSED DURING: 15 growth stages;CONTAINS InterPro DOMAIN/s: Light chain 3 (LC3) (InterPro:IPR004241);BEST Arabidopsis thaliana protein match is: Ubiquitin-like superfamily protein (TAIR:AT4G04620.2);Has 1531 Blast hits to 1529 proteins in 269 species: Archae - 0;Bacteria - 0;Metazoa - 726;Fungi - 172;Plants - 305;Viruses - 3;Other Eukaryotes - 325 (source: NCBI BLink).;AUTOPHAGY-RELATED 8A
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Involved Pathway
APG8A involved in several pathways and played different roles in them. We selected most pathways APG8A participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with APG8A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
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Protein Function
APG8A has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by APG8A itself. We selected most functions APG8A had, and list some proteins which have the same functions with APG8A. You can find most of the proteins on our site.
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Interacting Protein
APG8A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with APG8A here. Most of them are supplied by our site. Hope this information will be useful for your research of APG8A.
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