APBB3
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Official Full Name
amyloid beta (A4) precursor protein-binding, family B, member 3 -
Overview
The protein encoded by this gene is a member of the APBB protein family. It is found in the cytoplasm and binds to the intracellular domain of the Alzheimers disease beta-amyloid precursor protein (APP) as well as to other APP-like proteins. It is thought that the protein encoded by this gene may modulate the internalization of APP. Multiple transcript variants encoding several different isoforms have been found for this gene. -
Synonyms
APBB3;amyloid beta (A4) precursor protein-binding, family B, member 3;amyloid beta A4 precursor protein-binding family B member 3;FE65L2;Amyloid beta A4 precursor protein binding family B member 3;amyloid beta precursor protein binding family B member 3;amyloid precursor interacting protein;APBB3_HUMAN;Fe65 like protein 2;MGC150555;MGC87674;Protein Fe65-like 2;SRA;FE65-like protein 2
Recombinant Proteins
- Human
- Rat
- Rhesus macaque
- E.coli
- E.Coli or Yeast
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- GST
- His
- His&T7
- Non
- His&Fc&Avi
Involved Pathway
APBB3 involved in several pathways and played different roles in them. We selected most pathways APBB3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with APBB3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
APBB3 has several biochemical functions, for example, beta-amyloid binding,protein binding,transcription factor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by APBB3 itself. We selected most functions APBB3 had, and list some proteins which have the same functions with APBB3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| beta-amyloid binding | APBA2,CLSTN1,FBXO2,IDE,SORL1,Apba1,COL25A1,APOE,PION,BACE2 |
| protein binding | LTBP2,MNDA,LYRM2,ERGIC1,SOX30,SH3RF2,NUFIP2,GIMAP5,EXOSC2,C12orf43 |
| transcription factor binding | TRAPPC2,CAMTA2,POU5F1,Trl,MDFIC,EP300,HES1,CEBPA,HAND1,SOX10 |
Interacting Protein
APBB3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with APBB3 here. Most of them are supplied by our site. Hope this information will be useful for your research of APBB3.
DAPP1;PDPK1;EGFR;ERBB2;APP;RAB4A;APLP2
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References
