APBB2
-
Official Full Name
amyloid beta (A4) precursor protein-binding, family B, member 2 -
Overview
The protein encoded by this gene interacts with the cytoplasmic domains of amyloid beta (A4) precursor protein and amyloid beta (A4) precursor-like protein 2. This protein contains two phosphotyrosine binding (PTB) domains, which are thought to function in signal transduction. Polymorphisms in this gene have been associated with Alzheimers disease. Alternative splicing results in multiple transcript variants. -
Synonyms
APBB2;amyloid beta (A4) precursor protein-binding, family B, member 2;amyloid beta A4 precursor protein-binding family B member 2;Fe65 like;FE65L;FE65L1;MGC35575;Amyloid beta (A4) precursor protein-binding, family B, member 2 (Fe65 like);Amyloid beta A4 precursor protein binding family B member 2;APBB 2;APBB2_HUMAN;Fe65 like protein;FE65L 1;Protein Fe65-like 1;Rirl 1;Rirl1;TR2 L;TR2L;Zfra;Zinc finger like protein;Fe65-like 1;OTTHUMP00000218167;OTTHUMP00000218168;OTTHUMP00000218169;OTTHUMP00000218170;OTTHUMP00000218869;OTTHUMP00000218871;OTTHUMP00000218876;OTTHUMP00000218877;OTTHUMP00000218879
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| APBB2-670H | Recombinant Human APBB2 protein, GST-tagged | Wheat Germ | Human | GST |
|
|
| APBB2-8172H | Recombinant Human APBB2 protein, His & GST-tagged | E.coli | Human | His&GST | Asp413~Pro758 |
|
| APBB2-8802HCL | Recombinant Human APBB2 293 Cell Lysate | HEK293 | Human | Non |
|
Involved Pathway
APBB2 involved in several pathways and played different roles in them. We selected most pathways APBB2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with APBB2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
APBB2 has several biochemical functions, for example, beta-amyloid binding,protein binding,transcription factor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by APBB2 itself. We selected most functions APBB2 had, and list some proteins which have the same functions with APBB2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | RPLP0,KIF22,SCRIB,WDHD1,ATXN1,MID1IP1,BRIP1,SEPT12,KSR1,DNAJC11 |
| transcription factor binding | TAF7,HMGB2,DIP2A,SOX10,TMEM173,DR1,BRD7,KAT2B,NFATC3,BCOR |
| beta-amyloid binding | LDLRAD3,TSSK1B,CLSTN1,LDLRAP1,MAPK8IP2,GPRASP2,APOE,PION,Apba1,NGFR |
Interacting Protein
APBB2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with APBB2 here. Most of them are supplied by our site. Hope this information will be useful for your research of APBB2.
EGFR;APP;APLP2;HTT
Resources
Related Services
Related Products
References
