AOC3
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Official Full Name
amine oxidase, copper containing 3 (vascular adhesion protein 1) -
Overview
Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone;cofactor. The product is a major protein on the adipocyte plasma membrane. It has adhesive properties and also has;functional monoamine oxidase activity. A pseudogene for this gene has been discribed and is located approximately 9-kb;downstream. -
Synonyms
AOC3;amine oxidase, copper containing 3 (vascular adhesion protein 1);HPAO;SSAO;VAP1;VAP-1;membrane primary amine oxidase;copper amine oxidase;vascular adhesion protein 1;semicarbazide-sensitive amine oxidase;EC 1.4.3.21;EC 1.4.3;Vepalimomab;195158-85-1;Vapaliximab;336801-86-6
Recombinant Proteins
- Mouse
- Human
- Rat
- Mus musculus
- Sf21 Cells
- S.frugiperda
- Insect Cells
- CHO
- N-His
- Mammalian Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- E.coli
- Non
- His
- GST
- Avi
- Fc
Involved Pathway
AOC3 involved in several pathways and played different roles in them. We selected most pathways AOC3 participated on our site, such as Glycine, serine and threonine metabolism,Tyrosine metabolism,Phenylalanine metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with AOC3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Glycine, serine and threonine metabolism | SHMT2,CBSA,AOC2,PIPOX,AMT,GCSHB,GLDC,GAMT,GCSHA,PGAM2 |
| Tyrosine metabolism | DCT,TPO,AOX3L1,TYR,ALDH3B1,GOT2B,MAOB,AOX1,ADH2-1,GOT1 |
| Metabolic pathways | MAPK1IP1L,LIPT2,GOT2B,ASAH1B,SPR,ALDOA,AMPD3,RPN1,NDUFB6,CYP2C18 |
| Phenylalanine metabolism | IL4I1,MAOB,MAOA,ALDH3B1,TAT,AOC2,PAH,HPD,GOT2,GOT2A |
| beta-Alanine metabolism | SMS,ALDH6A1,ALDH2.1,HIBCH,ALDH7A1,ALDH3A2,ALDH3B2,HADHA,GAD1,ALDH2 |
Protein Function
AOC3 has several biochemical functions, for example, aliphatic-amine oxidase activity,aminoacetone:oxygen oxidoreductase(deaminating) activity,calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AOC3 itself. We selected most functions AOC3 had, and list some proteins which have the same functions with AOC3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | HMGB3,SHC3,RALGAPA1,LOX,HGS,NOP10,SPRED1,KLRC1,NDUFAF4,MAPT |
| protein homodimerization activity | PSPH,SEPT12,RPL7,HSP90AA1,AMICA1,GSTM3,BHLHB9,NR0B1,RENBP,LMLN |
| tryptamine:oxygen oxidoreductase (deaminating) activity | AOC2 |
| calcium ion binding | RPH3A,SCUBE2,PCDH15A,PLSCR1,OIT3,IHH,TMEM8C,PLA2G5,S100A6,SPARCL1 |
| primary amine oxidase activity | ABP1,MAOB,VCAM1,AOC1,MAOA,AOC2 |
| aliphatic-amine oxidase activity | AOC2 |
| protein heterodimerization activity | INHA,HIST1H4F,ATF4,TLR1,UGT1A6,IKBKB,HOMER1,RAB3GAP2,APITD1,SPTAN1 |
| copper ion binding | ADNP,AOC1,LOXL2,ATP7A,PAM,S100A5,DBH,HEPHL1,F5,LOXL2B |
| quinone binding | AMOTL1,ETFDH,AOC1,SQRDL,NDUFS7,AOC2,NDUFS2,HHIPL1,HHIP,TP53I3 |
Interacting Protein
AOC3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AOC3 here. Most of them are supplied by our site. Hope this information will be useful for your research of AOC3.
MYBPC2;PRRG4
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