ANO7
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Official Full Name
anoctamin 7 -
Overview
This prostate-specific gene encodes a cytoplasmic protein, as well as a polytopic membrane protein which may serve as a target in prostate cancer diagnosis and immunotherapy. Alternative splicing results in multiple transcript variants encoding different isoforms. -
Synonyms
ANO7;anoctamin 7;PCANAP5, TMEM16G, transmembrane protein 16G;anoctamin-7;IPCA 5;NGEP;PCANAP5L;transmembrane protein 16G;prostate cancer associated protein 5;Dresden-transmembrane protein of the prostate;DTMPP;IPCA5;D-TMPP;IPCA-5;PCANAP5;TM
Recombinant Proteins
- Mouse
- Rat
- Human
- Mammalian Cells
- HEK293
- His
- Non
- Avi
- Fc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ANO7-1702M | Recombinant Mouse ANO7 Protein | Mammalian Cells | Mouse | His |
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| ANO7-682R | Recombinant Rat ANO7 Protein | Mammalian Cells | Rat | His |
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| ANO7-8844HCL | Recombinant Human ANO7 293 Cell Lysate | HEK293 | Human | Non |
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| ANO7-338R | Recombinant Rat ANO7 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | Avi&Fc&His |
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| ANO7-338R-B | Recombinant Rat ANO7 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| ANO7-571M | Recombinant Mouse ANO7 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| ANO7-571M-B | Recombinant Mouse ANO7 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
ANO7 involved in several pathways and played different roles in them. We selected most pathways ANO7 participated on our site, such as Ion channel transport,Stimuli-sensing channels,Transmembrane transport of small molecules, which may be useful for your reference. Also, other proteins which involved in the same pathway with ANO7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Transmembrane transport of small molecules | ATP1A1A.3,TRPM4A,CLCN4,ANO9,TRPC4APB,FTH1B,SLC35B2,SLC22A7,ATP10A,SLC41A1 |
| Stimuli-sensing channels | TTYH3B,TRPM6,WNK1,ASPH,TRPC4B,Ano3,MCOLN3,SRI,TRPA1A,ANO8 |
| Ion channel transport | TRPM1A,ASIC1A,GLRBA,WWP1,ATP13A5,SLC17A3,TRPC5,WNK1,TTYH3B,FXYD6 |
Protein Function
ANO7 has several biochemical functions, for example, intracellular calcium activated chloride channel activity,NOT intracellular calcium activated chloride channel activity,phospholipid scramblase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ANO7 itself. We selected most functions ANO7 had, and list some proteins which have the same functions with ANO7. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| intracellular calcium activated chloride channel activity | CLCA2,ANO8,ANO4,ANO9,NMUR2,ANO6,CLCA4,ANO2,CLCA1,TTYH3 |
| NOT intracellular calcium activated chloride channel activity | ANO9,ANO10,ANO6,Ano3,ANO5,ANO8 |
| phospholipid scramblase activity | PLSCR3,ANO6,ANO4,Ano3,ANO9,PLSCR4,PLSCR1,PLSCR3A,PLSCR3B,PLSCR2 |
| protein dimerization activity | BTRC,HIF1AL,HES2,NHLH2,HER6,NPAS1,SMG1,MEF2CA,OLIG1,PPP3CA |
Interacting Protein
ANO7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ANO7 here. Most of them are supplied by our site. Hope this information will be useful for your research of ANO7.
Resources
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References
- Ousingsawat, J; Wanitchakool, P; et al. Anoctamin 6 mediates effects essential for innate immunity downstream of P2X(7) receptors in macrophages. NATURE COMMUNICATIONS 6:-(2015).
- Mazzone, A; Gibbons, SJ; et al. Identification and characterization of a novel promoter for the human ANO1 gene regulated by the transcription factor signal transducer and activator of transcription 6 (STAT6). FASEB JOURNAL 29:152-163(2015).
