ANKH
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Official Full Name
ankylosis, progressive homolog (mouse) -
Overview
This gene encodes a multipass transmembrane protein that is expressed in joints and other tissues and controls pyrophosphate levels in cultured cells. Progressive ankylosis-mediated control of pyrophosphate levels has been suggested as a possible mechanism regulating tissue calcification and susceptibility to arthritis in higher animals. Mutations in this gene have been associated with autosomal dominant craniometaphyseal dysplasia. -
Synonyms
ANKH;ankylosis, progressive homolog (mouse);ankylosis, progressive (mouse) homolog , CCAL2, CMDJ, craniometaphyseal dysplasia, Jackson type (dominant);progressive ankylosis protein homolog;ANK;CPPDD;HANK;Ankylosis progressive homolog (mouse);Ankylosis progressive homolog;CCAL 2;CCAL2;CMDJ;Craniometaphyseal dysplasia Jackson type (dominant);FLJ27166;MANK;OTTHUMP00000115641
Recombinant Proteins
- Chicken
- Rhesus macaque
- Human
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ANKH-1934C | Recombinant Chicken ANKH | Mammalian Cell | Chicken | His |
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| ANKH-325R | Recombinant Rhesus monkey ANKH Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| ANKH-564H | Recombinant Human ANKH protein, GST-tagged | Wheat Germ | Human | GST |
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| ANKH-8861HCL | Recombinant Human ANKH 293 Cell Lysate | HEK293 | Human | Non |
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| ANKH-1246HF | Recombinant Full Length Human ANKH Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 492 amino acids |
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| ANKH-153R | Recombinant Rhesus Macaque ANKH Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| ANKH-153R-B | Recombinant Rhesus Macaque ANKH Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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Involved Pathway
ANKH involved in several pathways and played different roles in them. We selected most pathways ANKH participated on our site, such as Miscellaneous transport and binding events,Transmembrane transport of small molecules, which may be useful for your reference. Also, other proteins which involved in the same pathway with ANKH were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Miscellaneous transport and binding events | CTNS,MRS2,ANKHA,PIP,AZGP1,ADD3A,ADD2,NIPA1,NIPAL3,EPB49 |
| Transmembrane transport of small molecules | SLC38A4,SLC5A2,ATP1A1A.2,ANO7,NHEDC1,SLC14A1,SLC35B4,SLC30A5,MFSD7B,SLC43A2B |
Protein Function
ANKH has several biochemical functions, for example, inorganic diphosphate transmembrane transporter activity,inorganic phosphate transmembrane transporter activity,phosphate ion transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ANKH itself. We selected most functions ANKH had, and list some proteins which have the same functions with ANKH. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| inorganic phosphate transmembrane transporter activity | SLC20A1A,SLC20A1,SLC17A7,SLC20A1B,SLC20A2 |
| phosphate ion transmembrane transporter activity | ANKHA,ANKHB,SLC17A1 |
Interacting Protein
ANKH has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ANKH here. Most of them are supplied by our site. Hope this information will be useful for your research of ANKH.
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