ANGPTL2
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Official Full Name
angiopoietin-like 2 -
Overview
Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and angiopoietin-4 participate in the formation of blood vessels. ANGPTL2 protein is a secreted glycoprotein with homology to the angiopoietins and may exert a function on endothelial cells through autocrine or paracrine action. [provided by RefSeq, Jul 2008] -
Synonyms
ANGPTL2;angiopoietin-like 2;ARP2;HARP;angiopoietin-related protein 2;angiopoietin-like protein 2
Recombinant Proteins
- Mouse
- Human
- Rat
- Chicken
- HEK293
- Insect Cell
- Mouse myeloma cell line
- E.coli
- Mammalian Cell
- Wheat Germ
- Human Cell
- In Vitro Cell Free System
- Mammalian cells
- His
- Flag
- His&Avi
- Fc
- His&T7
- GST
- Non
- His&SUMO
- His&Fc&Avi
Involved Pathway
ANGPTL2 involved in several pathways and played different roles in them. We selected most pathways ANGPTL2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ANGPTL2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
ANGPTL2 has several biochemical functions, for example, receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ANGPTL2 itself. We selected most functions ANGPTL2 had, and list some proteins which have the same functions with ANGPTL2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| receptor binding | H2-Q10,GFRA3,AMN,FGF12A,PTK6B,CHRNA10,ZAP70,NRG2,FGF10B,HIST2H3C2 |
Interacting Protein
ANGPTL2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ANGPTL2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ANGPTL2.
ITGB5;ITGB1;AURKA;TGFB1;ESR1;FGFR4;CDKN2A;CDKN2C;CASP8;FBXW7;BRMS1;RAC1;PTK2
Resources
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References
- Sato, R; Yamasaki, M; et al. Angiopoietin-like protein 2 induces androgen-independent and malignant behavior in human prostate cancer cells. ONCOLOGY REPORTS 33:58-66(2015).
- Deng, M; Lu, ZG; et al. A motif in LILRB2 critical for Angptl2 binding and activation. BLOOD 124:924-935(2014).
