ANAPC7
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Official Full Name
anaphase promoting complex subunit 7 -
Overview
This gene encodes a tetratricopeptide repeat containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for proper protein ubiquitination function of APC/C and for the interaction of APC/C with certain transcription coactivators. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008] -
Synonyms
ANAPC7;anaphase promoting complex subunit 7;APC7;anaphase-promoting complex subunit 7;cyclosome subunit 7
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- E.coli
- Mammalian Cells
- Wheat Germ
- In Vitro Cell Free System
- HEK293
- GST
- His
- DDK
- Myc
- Avi
- Fc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ANAPC7-9640H | Recombinant Human ANAPC7, GST-tagged | E.coli | Human | GST | C-term-302a.a. | |
| ANAPC7-1626M | Recombinant Mouse ANAPC7 Protein | Mammalian Cells | Mouse | His |
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| ANAPC7-547H | Recombinant Human ANAPC7 protein, GST-tagged | Wheat Germ | Human | GST |
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| ANAPC7-6323Z | Recombinant Zebrafish ANAPC7 | Mammalian Cells | Zebrafish | His |
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| ANAPC7-1286HF | Recombinant Full Length Human ANAPC7 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 503 amino acids |
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| Anapc7-1623M | Recombinant Mouse Anapc7 Protein, Myc/DDK-tagged | HEK293 | Mouse | DDK&Myc |
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| ANAPC7-2084H | Recombinant Human ANAPC7 Protein, MYC/DDK-tagged | HEK293 | Human | DDK&Myc |
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| ANAPC7-3228H | Recombinant Human ANAPC7 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | DDK&Myc |
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| ANAPC7-523M | Recombinant Mouse ANAPC7 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| ANAPC7-523M-B | Recombinant Mouse ANAPC7 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
ANAPC7 involved in several pathways and played different roles in them. We selected most pathways ANAPC7 participated on our site, such as Cell cycle,Oocyte meiosis,Ubiquitin mediated proteolysis, which may be useful for your reference. Also, other proteins which involved in the same pathway with ANAPC7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Progesterone-mediated oocyte maturation | RPS6KA3A,CPEB3,MAPK10,AKT2,PGR,CPEB4,INS2,PRKACBB,GNAI2,MAPK8A |
| Ubiquitin mediated proteolysis | UBE2W,TRIM37,UBE4A,BRCA1,TRIM32,NHLRC1,UBE2I,ITCH,CUL1A,UBE3A |
| HTLV-I infection | NFYB,FZD6,ANAPC4,PIK3R5,Pdgfa&Pdgfb,CRTC1,IL6,WNT7B,WNT16,PDGFB |
| Oocyte meiosis | BTRC,CAMK2A,FBXW11,SKP1,PRKACA,YWHAQB,BUB1,PRKACG,PLK1,YWHAG |
| Cell cycle | CENPJ,BORA,CCND2,ORC5,ODF2,CENPL,TGFB2,MCM6,CDKN1BB,CEP164 |
Protein Function
ANAPC7 has several biochemical functions, for example, protein phosphatase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ANAPC7 itself. We selected most functions ANAPC7 had, and list some proteins which have the same functions with ANAPC7. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein phosphatase binding | ERBB2,SHOC2,JAK1,PPP1R3G,KCNN4,CSF1R,CTNNB1,VCP,FGF19,PPARG |
Interacting Protein
ANAPC7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ANAPC7 here. Most of them are supplied by our site. Hope this information will be useful for your research of ANAPC7.
BUB1B;Cdc23;Cdc16;Cdc26;Anapc16;Cdc20;CDC23;Cdk1;CDC16
Resources
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References
- Ho, AW; Garg, AV; et al. The Anaphase-Promoting Complex Protein 5 (AnapC5) Associates with A20 and Inhibits IL-17-Mediated Signal Transduction. PLOS ONE 8:-(2013).
